血清同型半胱氨酸与老年高血压患者左心室肥厚关系  

Relationship between serum homocysteine and left ventricular hypertrophy in elderly patients with hypertension

作　　者：马素霞[1] 张红[1] 张丽英[1] 倪诤 尚少红[1] 

机构地区：[1]首都医科大学石景山教学医院北京市石景山医院急诊科,北京100050

出　　处：《中华实用诊断与治疗杂志》2016年第1期60-61,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：北京市优秀人才资助项目(20140000204400001)

摘　　要：目的探讨老年高血压患者血清同型半胱氨酸(homocysteine,Hcy)水平与左心室肥厚的关系。方法 131例老年高血压患者,依据血清Hcy水平分为2组,其中H型高血压组65例,非H型高血压组66例;对2组行心脏彩超检查,比较2组左心室质量指数。结果H型高血压组左心室质量指数[(134.1±29.8)g/m^2]高于非H型高血压组[(117.8±27.9)g/m^2],差异有统计学意义(P<0.01)。结论血清Hcy水平增高可加重老年高血压患者的左心室肥厚。Objective To explore the relationship between serum homocysteine （Hcy） and left ventricular hypertrophy in elderly patients with hypertension. Methods A total of 131 elderly patients with hypertension were divided into high-Hcy group （n=65） and normal-Hcy group （n=66）. Echocardiography was performed to compare the left ventricular mass index between two groups. Results The left ventricular mass index was significantly higher in high-Hcy group （（134.1± 29.8） g/m2） than that in normal Hcy group （（117.8±27.9） g/m2） （P〈0.01）. Conclusion The left ventrieular mass index increases in high-Hcy patients, and high-Hcy level aggravates the risk of left ventricular hypertrophy in elderly patients with hypertension.

关 键 词：高血压 同型半胱氨酸 左心室肥厚 老年人 

分 类 号：R544.1[医药卫生—心血管疾病]