超声实时弹性成像技术在甲状腺结节鉴别诊断中的价值  

Value of real-time elastosonography to the differential diagnosis of benign and malignant thyroid nodules

作　　者：顾继英[1] 金利芳[1] 姜露莹[1] 高康[1] 刘龙[1] 邵春娟[1] 张会萍[1] 史秋生[1] 杜联芳[1] 

机构地区：[1]上海交通大学附属第一人民医院超声科,上海200080

出　　处：《中华实用诊断与治疗杂志》2016年第1期62-64,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：国家自然科学基金青年项目(81301232;81201100);上海市卫生局基金(20124205)

摘　　要：目的探讨超声实时弹性成像技术在甲状腺良、恶性结节鉴别诊断中的价值。方法对74例甲状腺结节患者共96个结节的超声弹性图像进行分析,比较超声弹性成像评分法及应变率(strain ratio,SR)比值法对甲状腺良、恶性结节的诊断价值。结果组织病理证实96个结节中良性结节55个,恶性结节41个;超声弹性图像评分≥4分诊断恶性结节的敏感性、特异性、阳性预测值、阴性预测值、准确率分别为68.29%、90.91%、84.85%、79.37%、81.25%;SR比值法诊断甲状腺恶性结节的最佳界值为2.850,以SR≥2.850诊断甲状腺恶性结节的敏感性、特异性、阳性预测值、阴性预测值、准确率分别为80.49%,89.09%,84.62%,85.96%,85.42%,2种方法比较差异无统计学意义(P>0.05)。结论超声弹性成像评分法及SR比值法在甲状腺良、恶性结节鉴别诊断中均有重要价值。Objective To evaluate the value of real-time elastosonography to the differential diagnosis of benign and malignant thyroid nodules. Methods Ninety-six thyroid nodules in 74 patients underwent elastosonography, and were compared the values of ultrasound elastography score method and strain ratio （SR） method to the diagnosis of benign and malignant thyroid nodules. Results The histopathological results confirmed 55 benign thyroid nodules and 41 malignant nodules. When the score was 94, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate were 68.29%, 90. 91%, 84.85%, 79. 37% and 81.25% for malignant nodules, respectively. The cutoff point of SR method for malignant nodules was 2. 850 or larger, and the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate were 80.49%, 89.09%, 84.62%, 85.96% and 85.42%, respectively. There were no significant differences between two methods （P）0. 05 ）. Conclusion Both score and SR methods of elastosonography have values to the differential diagnosis of benign and malignant thyroid nodules.

关 键 词：甲状腺结节 超声 实时弹性成像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R581[医药卫生—诊断学]