唾液酸酶法在细菌性阴道病诊断中的应用价值  

Application value of sialidase test in diagnosis bacterial vaginosis

作　　者：刘惠容 

机构地区：[1]广东省惠州市惠阳区妇幼保健院检验科,广东惠州516211

出　　处：《中国当代医药》2016年第1期144-145,148,共3页China Modern Medicine

摘　　要：目的探讨唾液酸酶法对细菌性阴道病（BV）的诊断价值,并与传统Amsel法检测结果进行比较。方法选取2013年7月~2014年12月在本院就诊的1658例疑似BV患者,分别采用唾液酸酶法和Amsel法进行检查,并对两者结果进行比较。结果唾液酸酶法BV阳性检出率为35.0%,Amsel法为36.1%,两者差异无统计学意义（P〉0.05）;与传统Amsel法相比,唾液酸酶法筛查BV的灵敏度（94.5%）、特异度（98.2%）、总符合率（96.7%）、阳性预测值（94.5%）、阴性预测值（98.2%）均较高,假阴性率（5.5%）和假阳性率（1.9%）均较低。结论唾液酸酶法对BV的诊断具有简便、快速、敏感性和特异性高的特点,有较好的临床应用价值,可替代传统Amsel法用于妇产科门诊患者的BV筛查,值得推广应用。Objective To explore the diagnosis value of sialidase test in bacterial vaginosis（BV）,and to compare with the testing result of traditional Amsel method. Methods 1658 patients with suspected BV in our hospital from July2013 to December 2014 were selected.They were respectively tested with sialidase test and Amsel method,and the results were compared. Results BV positive detection rate of sialidase test was 35.0%,and in the Amsel method was36.1%,there was no significant difference between the two methods（P 〉0.05）.Compared with the traditional Amsel method,the sensitivity（94.5%）,specificity（98.2%）,total coincidence rate（96.7%）,positive predicted value（94.5%） and negative predicted value（98.2%） in sialidase test for BV sensitivity wer higher,false negative rate（5.5%） and false positive rate（1.9%） in sialidase test were lower. Conclusion Sialidase test in diagnosis bacterial vaginosis have features of simple and convenient,fast and high sensitivity and specificity,and has preferable clinical application value.It can replace the traditional Amsel method for the BV screening in obstetrics and gynecology clinic,and is worth popularizing.

关 键 词：唾液酸酶法 细菌性阴道病 AMSEL法 

分 类 号：R711.31[医药卫生—妇产科学]