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作 者:贾蕾[1] 王小莉[1] 吴双胜[1] 马建新[2] 李洪军[3] 高志勇[1] 王全意[1]
机构地区:[1]北京市疾病预防控制中心北京市预防医学研究中心传染病地方病控制所,100013 [2]北京市朝阳区疾病预防控制中心传染病地方痛控制科,100021 [3]北京市通州区疾病预防控制中心传染病地方,101100
出 处:《中华流行病学杂志》2016年第1期102-105,共4页Chinese Journal of Epidemiology
基 金:北京市自然科学基金(7132045)
摘 要:目的构建调整Serfling回归模型,估计北京市2011年至2015年5月23日病毒性腹泻相关〈5岁儿童超额腹泻病例数。方法利用北京市2家儿童专科医院〈5岁儿童急性腹泻周就诊病例数,拟合调整Serfling回归模型,估计其病毒性腹泻相关超额病例数。结果北京市2011年第8—10周、40~42周,2012年第40~46周,2013年第43~49周,2014年第45周直到2015年第11周为病毒性腹泻流行周。2家儿童专科医院各年度流行周〈5岁儿童病毒性腹泻相关超额就诊病例数分别为911(95%C1:26I~i56I)、l998(95%CI:l250—2746)、1645(95%c,:891~2397)、2806(95%CI:1938—3674)、1822(95%CI:614~3031)例,分别占同期全部〈5岁儿童腹泻就诊病例数的40.38%(95%CI:11.57%~69.19%)、44.21%(95%CI:27.66%一60.77%)、45.08%(95%c,:24.42%一65.69%)、60.87%(95%CI:42.04%~79.70%)和66.62%(95%CI:22.45%~110.82%)。估计北京市2011年至2015年5月23日〈5岁儿童病毒性腹泻相关超额就诊病例数为18731(95%CI:10106—27354)例。结论冬季是〈5岁儿童病毒性腹泻发病及就诊高峰。调整Serfling回归模型提示:应关注致急性胃肠炎病毒,尤其是诺如病毒的病原学变化。Objective To estimate the excess numbers of viral diarrheal cases among children aged 〈5 years in Beijing from I January 2011 to 23 May 2015. Methods The excess numbers of diarrheal cases among the children aged 〈5 years were estimated by using weekly outpatient visit data from two children' s hospital in Beijing and adjusted Serfling regression model. Results The incidence peaks of viral diarrhea were during 8^th-10^th week and 40^th-42^nd week in 2011, 40^th-46^th week in 2012, 43^rd-49^th week in 2013 and 45^th week in 2014 to 11^th week in 2015 respectively. The excess numbers of viral diarrheal cases among children aged 〈5 years in the two children's hospital were 911(95%CI: 261-1 561), 1 998(95%CI: 1 250-2 746), 1 645 (95%CI: 891-2 397), 2 806(95%CI: 1 938-3 674) and 1 822(95% CI: 614-3 031) respectively, accounting for 40.38% (95% CI: 11.57%-69.19%), 44.21%(95%CI: 27.66%-60.77%), 45.08%(95%CI: 24.42%-65.69%), 60.87% (95%CI: 42.04%-79.70%) and 66.62% (95%CI: 22.45%-110.82%) of total outpatient visits due to diarrhea during 2011-2015, respectively. Totally, the excess number of viral diarrheal cases among children aged 〈5 years in Beijing was estimated to be 18 731(95%CI: 10 106-27 354) from 2011 to 23 May 2015. Conclusions Winter is the season of viral diarrhea for children aged 〈5 years. The adjusted Serfling regression model analysis suggested that close attention should be paid to the etiologic variation of viruses causing acute gastroenteritis, especially the etiologic variation of norovirus.
关 键 词:病毒性腹泻 调整Serfling回归模型 超额病例数
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