口腔颌面部间隙感染患者多药耐药菌分析  

Analysis of pathogenic bacteria distribution and drug resistance in oral and maxillofacial infection

作　　者：徐贤寅[1] 沈波[2] 林莉莉[3] 

机构地区：[1]南京医科大学附属无锡人民医院口腔科,江苏无锡214023 [2]南京医科大学附属无锡人民医院医院感染管理处,江苏无锡214023 [3]无锡卫生高等职业技术学校药学系,江苏无锡214028

出　　处：《中国临床药理学杂志》2016年第1期27-29,共3页The Chinese Journal of Clinical Pharmacology

摘　　要：目的观察口腔颌面部感染的多药耐药菌,为临床感染的控制提供相关的依据。方法口腔科共送检感染标本51例,检出多药耐药菌10株,与同期医院检出的多药耐药菌种类及耐药情况进行比较,用SPSS 19.0软件进行统计分析。结果口腔颌面部感染的多药耐药菌10株,以革兰阳性菌为主(占80.00%),革兰阴性菌占20.00%;同期全院检出多药耐药菌1773株,革兰阳性菌431株(占24.31%),革兰阴性菌1342株(占75.69%)。口腔科金黄色葡萄球对青霉素,克林霉素,红霉素有较高的耐药性,与全院检出的金黄色葡萄球菌耐药性比较,差异无统计学意义(P>0.05)。结论口腔颌面部感染多药耐药菌以革兰阳性菌为主,应对病原菌和耐药性进行检测与分析,合理选用抗菌药物。Objective To observe the multi-drug resistant bacteria in oral and maxillofacial space infection,so as to provide the basis for the control of clinical infections. Methods A total of 51 cases of patients with oral and maxillofacial infection were selected,and a total 10 strains of the multi-drug resistant bacteria were detected. The antibiotic susceptibility tests were carried out. The species and drug resistance of the bacteria were compared with that of the multi-drug resistant bacteria detected during the same period in our hospital. Statistical analysis of the data was carried out with the software SPSS19. 0. Results The main multi-drug resistant bacteria in oral and maxillofacial infection were gram-positive bacteria accounting for 80. 00%,and gram-negative bacteria accounting for 20. 00%. During the same period in our hospital,1773 strains of multi-drug resistant bacteria were isolated. A total of 431 strains were gram-positive bacteria accounting for 24. 31%,and 1342 strains were gram-negative bacteria accounting for 75. 69%. The Staphylococcus aureus in oral and maxillofacial infection were highly resistant to penicillin,clindamycin and erythromycin. There was no significant difference in the drug resistance between pathogenic bacteria in oral and maxillofacial region and those in our hospital. Conclusion Gram positive bacteria were the main multi-drug resistant bacteria in oral and maxillofacial region infection. In the treatment,pathogenic bacteria detection and antibiotic susceptibility tests should be performed in time,so as to make the use of antibiotics more reasonably in clinic.

关 键 词：口腔颌面部 多药耐药菌 感染 

分 类 号：R969.3[医药卫生—药理学] R978.1[医药卫生—药学]