5-氨基酮戊酸光动力疗法联合强脉冲光及LED红光治疗中、重度痤疮疗效观察  

Efficacy of 5-ALA Photodynamic Therapy Combined with IPL and LED Red Light in the Treatment of Moderate and Severe Acne

作　　者：米希婷[1] 鲍海平[1] 郑爱义[1] 米亚英[1] 王娟[1] 武晓华[1] 

机构地区：[1]山西大同大学医学院,山西大同037009

出　　处：《山西大同大学学报（自然科学版）》2015年第6期44-46,共3页Journal of Shanxi Datong University(Natural Science Edition)

摘　　要：目的评价5-氨基酮戊酸光动力技术（ALA-PDT）联合强脉冲光（IPL）和LED红光治疗中、重度痤疮的效果,探讨痤疮治疗的最佳方案。方法用ALA-PDT治疗痤疮21例,治疗3-4次;用ALA-PDT联合IPL治疗痤疮30例,先用ALA-PDT治疗3次后,改用IPL治疗1-2次;用ALA-PDT联合二极管激发（LED）红光治疗痤疮29例,先用ALA-PDT治疗3次后,改用LED红光治疗2-4次。分别于治疗6周、8周及治疗后3月对3种方法治疗痤疮的疗效进行评价,并记录不良反应。结果 3种治疗方法于治疗6周、8周及疗后3月的总有效率分别为：ALA-PDT组,76.19%,85.71%,90.48%;ALA-PDT联合IPL组,86.67%,96.67%,96.67%;ALA-PDT联合LED红光组,65.52%,68.97%,65.52%。结论 ALA-PDT联合IPL和ALA-PDT二法治疗中、重度痤疮均有较好疗效,但ALA-PDT联合IPL较ALA-PDT具有简化程序、不良反应小等优点,值得临床推广应用。Objective To evaluate the effect of 5-ALA-PDT combined with IPL and LED red light in the treatment of moderate and severe acne. Methods ALA-PDT treatment of 21 cases of acne, treated 3-4times. ALA-PDT combined with IPL for treatment of30 cases of acne. First, treated with ALA-PDT 3 times, and then switch to IPL 1-2 times. AL-PDT combined with LED red light for treatment of 29 cases of acne. First, treated with ALA-PDT 3 times, and then switch to LED red light treated 2-4 times. Estimate the efficacy of three methods of treatment for 6 weeks, 8 weeks and 3 month after treatment being evaluated, and recorded the adverse reactions. Rusults The total effective rate of 6 weeks, 8 weeks and 3 months after treatment of the three treatments was： ALA-PDT group：76.19%, 85.71%, 90.48%; ALA-PDT combined with IPL group： 86.67%, 96.67%, 96.67%; AL-PDT combined with LED red light group： 65.52%, 68.97%, 65.52%. Conclusions Both ALA-PDT and ALA-PDT combined with IPL method have good efficacy in treatment of moderate and severe acne. But ALA-PDT combined with IPL has the advantages of simplified procedures, adverse reactions,etc. Witch is worthy to clinical application.

关 键 词：痤疮 ALA-PDT IPL LED红光 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]