纳米羟基磷灰石/聚酰胺6医用复合材料的制备及性能表征  

Preparation and properties characterization of nano hydroxyapatite/polyamide 6 biomedical composites

作　　者：冯娇[1] 刘海蓉[2] 李永生[2] 苏伟[1] 孙业熙 阮建明[1] 

机构地区：[1]中南大学粉末冶金国家重点实验室,长沙410083 [2]湖南大学材料科学与工程学院,长沙410083

出　　处：《复合材料学报》2015年第6期1602-1610,共9页Acta Materiae Compositae Sinica

基　　金：国家自然科学基金(51274247);中南大学研究生自主探索创新项目(2014zzts177)

摘　　要：为防止纳米羟基磷灰石(nano HAP)粉末的团聚,采用溶剂沉淀法制备了nano HAP/聚酰胺6(PA6)复合粉末,并对粉末进行热压成型制得nano HAP/PA6复合材料。然后,通过FTIR、XRD和SEM对nano HAP/PA6复合材料的成分、结构和形貌进行了表征,并对复合材料的热稳定性、力学性能和细胞相容性进行了检测。结果表明:所制备的nano HAP/PA6复合材料结晶体大小均匀,且PA6只存在α型结晶;由于nano HAP与PA6界面上形成新的氢键和COO—Ca,复合材料具有良好的综合性能;在低于350℃时,nano HAP/PA6复合材料不会发生裂解,力学性能与人骨匹配,50wt%nano HAP/PA6复合材料的弯曲强度、压缩强度和弹性模量分别为146.87MPa、98.44MPa和5.44GPa。MG-63骨瘤细胞在nano HAP/PA6复合材料表面粘附和生长状况良好,说明nano HAP/PA6复合材料具有良好的细胞相容性。所得结论表明nano HAP/PA6复合材料在骨修复方面具有应用价值。In order to prevent the conglomerating of nano hydroxyapatite（nano HAP）powders,the nano HAP/polyamide 6（PA6）composite powders were prepared by solvent precipitation method,and nano HAP/PA6 composites were obtained through hot-press forming of the powders.Then,the constituent,structure and morphology of nano HAP/PA6 composites were investigated using FTIR,XRD and SEM,and thermal stability,mechanical properties and cellular compatibility of composites were measured as well.The results show that the crystalline size of prepared nano HAP/PA6 composites is uniform,and PA6 only has the crystal ofαform.For new hydrogen bonds and COO—Ca forming on the interface of nano HAP and PA6,the composites have good synthetic performances.Nano HAP/PA6 composite does not split within 350℃,and the mechanical properties are close to human skeleton.The bending strength,compressive strength and elastic modulus of 50wt% nano HAP/PA6 composite are146.87 MPa,98.44 MPa and 5.44 GPa,respectively.The situations of MG-63 bone tumor cells attaching and growth on the surfaces of nano HAP/PA6 composites are good,which indicates the nano HAP/PA6 composites have good cellular compatibility.The conclusions obtainted show that nano HAP/PA6 composites have application values in bone repair aspect.

关 键 词：复合材料 纳米羟基磷灰石 聚酰胺6 溶剂沉淀法 性能 

分 类 号：TB332[一般工业技术—材料科学与工程]