304例大肠息肉患者相关代谢指标的临床研究  

Clinical study of metabolic parameters in 304 patients with colorectal polyps

作　　者：丁玲[1] 张伟华[1] 马靖[1] 巩艳[1] 马聪[1] 余秉翔[1] 

机构地区：[1]解放军总医院健康管理研究院国际部,北京100853

出　　处：《中华保健医学杂志》2015年第6期473-475,共3页Chinese Journal of Health Care and Medicine

摘　　要：目的初步分析体质量指数（body mass index，BMI）、血脂、血清尿酸等代谢指标与大肠息肉的相关性。方法收集2014年1月～2014年12月于解放军总医院健康管理研究院国际部行纤维结肠镜检查的患者1030例，其中行内镜下大肠息肉治疗术患者304例，相关指标分析包括性别、年龄、BMI、血清尿酸、非高密度脂蛋白胆固醇（nHDL—C）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL—C）、三酰甘油（TG）、脂蛋白a及病理分型，分别比较正常对照组与大肠息肉组、腺瘤与非腺瘤性息肉组间的情况。结果与正常对照组比较，大肠息肉组患者血清尿酸、BMI、年龄、HDL—C、nHDL—C水平两组间差异有统计学意义（P〈0．05）。不同病理类型息肉组间比较，腺瘤组血清尿酸、HDL—C、脂蛋白a水平明显高于非腺瘤组．差异有统计学意义（P〈0．05）。年龄、BMI、血清尿酸与大肠息肉的发生呈正相关。结论年龄、BMI、血清尿酸以及血脂异常与大肠息肉发生相关。Objective To analyze the correlation between the metabolic parameters including body mass index （BMI）,blood lipids, serum uric acid and eoloreetal polyps. Methods One thousand and thirty cases of patients who had eolonoseopy （304 of whom had been treated with endoscopic polypeetomy） in PLA General Hospital from Jan. 2014 to Dee. 2014, was chosen as research subjects. All the patients were divided into eolorectal polyps group and control group. According to the standard of pathological types of eoloreetai polyps, all the patients were divided into adenomatous polyps group and non-adenomatous polyps group. The indexes such as gender, age, BMI, serum uric acid, non-high-density lipoprotein cholesterol （nHDL-C）, total cholesterol （TC）, low- density lipoprotein cholesterol （LDL-C）, triglyeeride （TG）, lipoprotein （a） and pathological type were examined from these patients. The differences of these indexes between different groups were compared respectively. Results There were significant differences in the levels of serum uric acid, BMI, age, HDL-C, uHDL-C between eolorectal polyps group and control group （P 〈 0.05 ）. The levels of serum uric acid, HDL-C and ]ipoprotein （a） were significantly higher in adenomatous polyps group than that of non-adenomatous group（P 〈 0.05）. Age, B MI and serum uric acid had positive correlation with eoloreetal polyps. Conclusion Age, BMI, serum uric acid and dyslipidemia are associated with the risk of colorectal polyps.

关 键 词：大肠息肉 血脂 血清尿酸 体质量指数 

分 类 号：R574[医药卫生—消化系统]