等量间断和持续运动对轻中度高血压患者动态血压和血液流变性的影响  

Equal-volume interval and continuous physical exercise on dynamic blood pressure and hemorheology in mild and moderate hypertension

作　　者：王磊[1] 赵志刚[1] 高真真[1] 周方[1] 

机构地区：[1]南京中医药大学第二临床医学院,南京210046

出　　处：《中国康复医学杂志》2016年第1期45-49,76,共6页Chinese Journal of Rehabilitation Medicine

基　　金：全国高校博士点基金项目(20123237120008)

摘　　要：目的:比较总运动量相同的间断运动和持续运动对轻中度高血压患者动态血压和血液流变性的影响。方法:将60例经确诊的轻中度高血压患者随机分为对照组、间断运动组和持续运动组。对照组随意正常生活,不安排特定运动训练;间断运动组每天早、中、晚分3次分别进行20min强度为50%VO2peak步行运动;持续运动组每晚进行60min相同强度步行运动。运动训练前以及12周运动训练结束之后,监测所有参与者24h的动态血压以及血液流变性变化。观察分析12周运动训练前后的血压和血液流变性变化,并分析两者之间的关系。结果:对照组各项血压指标在运动训练前后差异无显著性意义(P>0.05)。训练后组内比较,间断运动组收缩压平均下降了12mm Hg,舒张压平均下降了5.8mm Hg;持续运动组收缩压平均下降了6.8mm Hg,舒张压下降了3.2mm Hg。间断运动组和持续运动组24h动态血压与运动训练前相比差异有显著性意义(P<0.05)。训练后组间比较,间断运动组在训练后24h动态血压下降更为明显,与持续运动组相比,差异有显著性意义(P<0.05)。对照组12周运动训练前后血液流变性各指标变化无显著性意义(P>0.05)。12周运动训练前后两个运动组的低切变率下全血黏度、高切变率下全血黏度、血浆比黏度以及红细胞压积的变化都有显著性差异(P<0.05),且间断运动组的血液流变性改善更加明显(P<0.05)。而ET、PAR和Fb虽然也出现下降趋势,但无显著性意义(P>0.05)。结论:间断运动和持续运动都可以降低轻中度高血压患者的血压以及改善患者的血液流变性,且间断运动的效果更好。Objective： To compare the effects of equal-volume interval physical exercise （IPE） and continuous physical ex- ercise （CPE） on dynamic blood pressure（BP） and hemorheology in patients with mild and moderate hyperten- sion. Method： Sixty patients with hypertension were randomly divided into 3 groups, a control group, IPE group and CPE group. The control group had no specific physical exercise and lived normally. The IPE group was conducted in three 20-min walk at 50% of VO2peak in the morning, at noon and at night respectively and the CPE group was conducted in 60-min walk at 50% of VO2peak at night. All participants＇ dynamic BP and hemorheology were monitored before and after 12 weeks exercise training. Result： There was no significant difference in blood pressure indexes before and after training in the control group （P〉0.05）. After training, the systolic blood pressure of IPE group decreased by 12mmHg, and the diastol-ic blood pressure decreased by 5.8mmHg; the systolic blood pressure of CPE group decreased by 6.8mmHg, and the diastolic blood pressure decreased by 3.2mmHg. Before and after training, there was significant differ- ence in 24h dynamic blood pressure between the IPE group and the CPE group. Compared with CPE group, the 24h dynamic blood pressure of CPE group decreased obviously after training, the difference was signifi- cant. There was no significant difference in blood hemorheology index（P〉0.05） before and after training in the control group（12 weeks）. The whole blood viscosity at low shear rate, the whole blood viscosity at high shear rate, plasma specific viscosity and hematocrit were significant different between the two groups before and af- ter the 12 week exercise, and the improvement of blood hemorheology in the IPE group was more obvious（P〈 0.05）. While ET, PAR and Fb were also decreased, but they had no significance（P〉 0.05）. Conclusion： The interval and single CPE could reduce BP and improve hemorheology in patients with mild and moderate

关 键 词：步行运动 高血压 动态血压 血液流变性 

分 类 号：R544.1[医药卫生—心血管疾病] R493[医药卫生—内科学]