陈美华以滋肾平肝、化痰活血法治疗原发性高血压的临床研究  

Clinical Study on Chen Meihua in Treating Essential Hypertension with Therapy of Nourishing kidney to Calm Liver and Activating Blood Circulation to Resolve Phlegm

作　　者：陈娟[1] 

机构地区：[1]福建中医药大学附属第二人民医院肾病科,福州350003

出　　处：《光明中医》2016年第2期202-205,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的观察陈美华主任以滋肾平肝、化痰活血法辨治原发性高血压的临床疗效。方法 70例原发性高血压患者随机分为治疗组和对照组各35例。两组均予西药降压治疗,治疗组加服中药以滋肾平肝、化痰活血。治疗4周后评价疗效。结果两组降压疗效比较:治疗组总有效率91.4%,与对照组比较,有统计学意义(P<0.05)。两组治疗前、后收缩压与舒张压均下降(P<0.01),但治疗组降压疗效更优于对照组(P<0.05)。两组临床症状疗效比较:两组治疗前、后症状积分均有改善(P<0.05);治疗组对于改善临床症状更优于对照组(P<0.05),尤其在改善眩晕、头重、胸闷、五心烦热、腰酸、肢体麻木方面更具有优势(P<0.05)。血液流变学疗效分析:治疗组治疗前、后比较血浆纤维蛋白原与血小板最大聚集率均有统计学差异(P<0.05);对照组治疗前、后比较血浆纤维蛋白原与血小板最大聚集率均无统计学差异(P>0.05)。治疗后两组间比较血浆纤维蛋白原与血小板最大聚集率均有统计学差异(P<0.05)。结论陈美华主任应用其经验方滋肾平肝、化痰活血治疗高血压病疗效良好,值得临床推广应用。Objective To observe the clinical effect of Chen Meihua in treating essential hypertension with therapy of nourishing kidney to calm liver and activating blood circulation to resolve phlegm. Methods 70 cases of patients with essential hypertension were randomly divided into treatment group and the control group, and each group had 35 cases. Both the two groups were given Western medicine to control blood pressure. The treatment group was given additionally Chinese medicine of nourishing kidney to cairn liver and activating blood circulation to resolve phlegm. The therapeutic effect was evaluated after treatment of 4 weeks. Results In the aspect of antihypertensive effect, the total effective rate of the treatment group was 91.4% , which had a statistically significant comparing with the control group （P 〈 0. 05）. After treatment, the systolic and diastolic blood pressure of the two groups significantly declined （P 〈 0. O1 ）, but the antihypertensive effect of the treatment group was better than that of the control group （P 〈 0.05）. In the aspect of clinical symptoms, both the two groups had improvement in symptom score （P 〈 0. 05 ） , while the improvement in symptom score of the treatment group was better than that of the control group （P 〈0.05） , especially in the improvement of vertigo, head weight, chest tightness, five upset hot, backache and numbness （P 〈 0.05）. In the aspect of hemorheological effect, after treatment, the treatment group can reduce the plasma fibrinogen and platelet maximum aggregation rates, and there was statistical difference （P 〈 0.05）. While the control group had no effect on reducing the plasma fibrinogen and platelet maximum aggregation rates （P 〉 0.05 ）. The difference between the two groups after treatment, on plasma fibrinogen and platelet aggregation rate were significantly different （P 〈 0. 05）. Conclusion Chen Meihua used her empirical prescription to treat essential hypertension with therapy of nourishing kidney to calm liv

关 键 词：原发性高血压 肝肾亏虚 痰瘀内阻 滋肾平肝 活血化痰 

分 类 号：R249[医药卫生—中医临床基础] R259[医药卫生—中医学]