体重指数对前列腺癌检出率及Gleason评分的影响  

Effect of boby mass index on positive rate of prostate cancer and Gleason score in the patients undergoing transrectal prostate biopsy

作　　者：周峰[1] 浦金贤[1] 欧阳骏[1] 李纲[1] 平季根[1] 裴昌松[1] 黄玉华[1] 侯建全[1] 

机构地区：[1]苏州大学附属第一医院泌尿外科,江苏省215006

出　　处：《江苏医药》2016年第1期17-19,共3页Jiangsu Medical Journal

基　　金：国家自然科学基金(81300478);江苏省自然科学基金(BK20130269);江苏省卫生厅医学科研项目(H201312);苏州市科学发展计划项目(SYS201450)

摘　　要：目的探讨前列腺穿刺活检患者的体重指数(BMI)对前列腺癌检出率及Gleason评分的影响。方法初次行经直肠前列腺穿刺活检患者290例分为高BMI组(BMI≥25 kg/m^2,143例)和正常BMI组(BMI<25 kg/m^2,147例)。回顾性分析Gleason评分、总前列腺特异抗原、BMI、年龄和种族等相关临床资料,比较前列腺癌检出率和Gleason评分的差异。结果290例前列腺穿刺活检患者中,前列腺癌137例。两组前列腺癌检出率相仿(48.95%vs.45.58%)(P>0.05);高BMI组的高Gleason评分(≥7分)比例高于正常BMI组(44.76%vs.38.10%)(P<0.05)。结论前列腺穿刺活检患者的BMI对前列腺癌检出率没有显著影响,但BMI是影响前列腺穿刺活检Gleason评分的重要因素。Objective To investigate the effect of body mass index（BMI） on the positive rate of prostate cancer and Gleason score in the patients undergoing transrectal prostate biopsy. Methods A total of 290 patients underwent prostatic biopsy for the first time was assigned into two groups of A（with BMI≥25 kg/m2, 143 cases） and B（with BMI〈25 kg/m2, 147 eases）. The data of Gleason score,total PSA,BMI, age, race were retrospectively analyzed. The prostate cancer positive rate and Gleason score were compared between two groups. Results Of 290 cases of prostate biopsy, 137 cases were diagnosed as prostate cancer. The prostate cancer positive rate of group A was similar to that of group B（48. 95% vs. 45.58%）（P〈0. 05）. The percentage of patients with high Gleason score （Gleason score≥7 points） was higher in group A than that in group B（44. 76%vs. 38. 10%） （P〈0. 05）. Conclusion There is no significant effect of BMI on the positive rate of prostate cancer by prostate biopsy. But BMI is an important factor influencing Gleason score of prostate biopsy.

关 键 词：体重指数 前列腺穿刺活检 GLEASON评分 前列腺癌 

分 类 号：R697[医药卫生—泌尿科学]