原发性高血压患者血压动态变化与靶器官损害的关系探讨  

Study on relationship between dynamic changes of blood pressure and target organ damage in patients with essential hypertension

作　　者：于爽 丁长青[2] 

机构地区：[1]江苏丰县博爱医院内科,丰县221700 [2]江苏丰县人民医院CT室,丰县221700

出　　处：《内科》2015年第6期778-779,828,共3页Internal Medicine

基　　金：徐州市医学青年后备人才工程资助(nw2014019)

摘　　要：目的探讨原发性高血压患者杓型和非杓型血压类型改变对靶器官损害的影响。方法选取原发性高血压患者56例为研究对象,采用德国费希尔动态血压监测仪对患者进行24 h动态血压监测,根据24 h动态高血压类型分为杓型组(28例)和非杓型组(28例),对两组患者进行冠脉血管造影(CTA)、头颅MRI、肾功能及眼底检查,比较两组患者靶器官损害情况。结果非杓型组患者靶器官损害程度较杓型组明显,差异有统计学意义(P<0.05)。结论动态血压监测可以预测高血压患者靶器官损害的情况,对高血压的防治具有重要临床意义。Objective To investigate the effect of target organ damage in dipper and non dipper type hypertension patients. Methods Twenty-four hour ambulatory blood pressure of 56 cases patients with essential hypertension was carried out by using ambulatory blood pressure monitoring, then the patients were divided into dipper group （28 cases） and non dipper group （28 cases） according to the type of blood pressure, and were detected coronary CTA, MRI and fundus examination and the target organ damage were compared between two groups. Results The extent of damage of target organ in dipper group was significantly milder than that of non dipper group（P 〈 0.05 ）. Conclusions Ambulatory blood pressure monitoring can predict target organ damage in patients with essential hypertension, and has important clinical significance for hypertension prevention and control.

关 键 词：高血压 非杓型 靶器官损害 

分 类 号：R544.11[医药卫生—心血管疾病]