334例药品不良反应的医院质控负性指标监控分析  

Monitorin Analysis of the Negative Index of Hospital Quality Control Based on 334 Cases of Adverse Drug Reaction Reports

作　　者：边永娜[1] 张田香[1] 任小烨[1] 高建民[2] 

机构地区：[1]西安交通大学医学院第一附属医院,陕西西安710061 [2]西安交通大学公共卫生学院,陕西西安710061

出　　处：《中国医院管理》2016年第1期68-69,共2页Chinese Hospital Management

基　　金：西安交通大学医学院第一附属医院软科学基金项目(2013YK3)

摘　　要：目的分析药品不良反应发生特点和分布规律,为临床合理用药提供指导及参考依据。方法采用回顾性分析,对2012—2013年西安交通大学医学院第一附属医院上报的药品不良反应进行统计分析。结果 2012年1月—2013年12月上报药品不良反应334例,其中以呼吸科上报例数最多,占18.3%(61/334);人群分布中,10岁以下儿童构成比占12.3%,60岁以上老人占30.5%;给药途径上,药品不良反应主要因注射剂引起的,达到78.7%;按药品分类,抗肿瘤药物和抗菌素引起的药品不良反应最多,分别为30.2%和29.6%;预后分析,96.1%的药品不良反应痊愈或好转。结论医院应加强药品不良反应监测,同时还要加快药品不良反应院内信息传递,合理用药,确保患者安全。Objective To provide the references and directions for clinical rational？drug use by analyzing the characteristics and distribution of drug reactions（ADRs） in our hospital. Methods The retrospective study was used to statistically analyze the 334 cases of ADRs which were reported in our hospital from 2012.1 to 2013.12. Results Of total 334 ADRs cases,the most cases were from the department of respiration,accounted for 18.3%（61/334）. According to the population distribution of the cases, there is 12.3% of children below 10 years old（41/334） and 30.5%（107/334） of senior more than 60 years old. About the route of administration, injection caused ADRs was up to 78.7%（263/334）;and in the classification of drugs,the most likely ADRs were caused by antitumor drugs and antibiotics,30.2% and 29.6%,respectively. 96.1% prognosis of ADRs have a good result. Conclusion In order to ensure patients safety, hospital should pay more attention to monitoring ADRs, strengthing the communication of ADRs information likewise and use drugs rationally.

关 键 词：药品不良反应 监测 合理用药 

分 类 号：R95[医药卫生—药学]