初发2型糖尿病患者谷氨酸脱羧酶抗体相关因素分析  

Analysis Related Factors of GADA Positive Cases in Newly Type 2 Diabetes Mellitus

作　　者：汪丽[1] 

机构地区：[1]安阳市人民医院,河南安阳455000

出　　处：《中外医学研究》2016年第1期14-16,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究初发2型糖尿病患者谷氨酸脱羧酶抗体(GADA)阳性率,并分析其临床特征。方法:测定213例初发2型糖尿病(DM)患者的身高、体重、血糖、C肽、GADA,对GADA阳性和阴性患者临床特征进行对比分析。结果:15例患者GADA阳性,GADA阳性患者具有体重指数偏低、血清C肽水平较低的特点。结论:对于体重指数偏低、血清C肽水平较低且无糖尿病家族史的初发糖尿病患者进行GADA筛查,有助于早期发现并诊断成人迟发性自身免疫性糖尿病(LADA)。Objective：To explore the positive rate of GADA and to analyze the clinical features in newly type 2 diabetes mellitus.Method：213 cases newly type 2 diabetes mellitus patients in our hospital outpatient were done with GADA examination and analyzed the clinical indicators.Result：15 patients of them were GADA positive.GADA positive patients had a lower body mass index,and the characteristics of the low level of serum C peptide.Conclusion：To screen GADA in newly type 2 diabetes mellitus patients who have a lower body mass index,low level of serum C peptide without family history of diabetes,help to detection and diagnosis of earlier late-onset autoimmune diabetes in adults（LADA）.

关 键 词：2型糖尿病 谷氨酸脱羧酶抗体 成人迟发性自身免疫性糖尿病 

分 类 号：R587.1[医药卫生—内分泌]