石榴抗肿瘤有效成分的研究进展  

Research Progress on Anti-tumor Effect of Pomegranate Effect Components

作　　者：谢莉[1] 田莉[1,2] 

机构地区：[1]新疆医科大学中医学院,乌鲁木齐830011 [2]新疆名医名方与特色方剂学重点实验室,乌鲁木齐830011

出　　处：《中国实验方剂学杂志》2016年第2期211-215,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(81260668);新疆医科大学"天山英才工程"项目(Y0382002)

摘　　要：石榴为药食同源的药材,具有抗肿瘤、抗炎、抗氧化、降血糖、降血压及预防心脑血管疾病等多种药理和生理作用。因此,近年来对石榴的研究与探索越来越受到世界各国相关领域的重视。在我国石榴栽培历史悠久,资源丰富,但目前国内学者对石榴的研究大多都集中在石榴多酚类或黄酮类的提取工艺报道、化学成分分离和体外药理作用等方面,对石榴中单体化合物抗肿瘤的研究方面报道较少。石榴中存在多种药效活性成分,包括鞣花酸、安石榴苷、没食子酸、石榴皮鞣素、石榴酸等。本文对其抗肿瘤作用药效成分单体化合物的研究进展进行了综述,以期为石榴抗肿瘤作用的后续研究提供参考。Pomegranate is the homology of medicine and food medicine,has the anti-tumor,antiinflammatory,anti-oxidation,fall blood sugar,blood pressure and prevent disease of heart head blood-vessel and so on the many kinds of pharmacological and physiological function. Therefore,in recent years,more and more research and exploration on pomegranate have drawn the attention of the related areas around the world.Pomegranate cultivation in our country has a long history and rich in resources,but at present domestic scholars of pomegranate research mostly focus on the extraction process of polyphenols and flavonoids reported separation,chemical composition and pharmacological action in vitro,etc.,the pomegranate monomer compounds in anti-tumor research reported less. There are many effective active ingredient in pomegranate, including Ellagic acid,pomegranate glycosides,gallic acid,pomegranate acid,etc. In this paper,the research progress on the antitumor efficacy composition monomer compounds were reviewed,in order to provide reference for pomegranate antitumor effect of follow-up studies.

关 键 词：石榴 抗肿瘤 有效成分 

分 类 号：R285.5[医药卫生—中药学]