多孔钽棒配合股骨头坏死愈胶囊治疗激素性股骨头坏死临床观察  

Treatment of Steroid-induced Osteonecrosis of Femoral Head by Porous Tantalum Rod and Gugutou Huaisiyu Capsule

作　　者：谭旭仪[1] 高菲菲[2] 高书图[2] 刘又文[2] 陈献韬[2] 刘立云[2] 

机构地区：[1]湖南中医药大学研究生院,长沙410208 [2]河南省洛阳正骨医院髋部损伤中心,河南471000

出　　处：《中国中西医结合杂志》2016年第1期40-43,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：河南省公益类科研院所预研计划资助项目(No.09yy0067);洛阳市应用科技与开发基金项目(No.1101058A)

摘　　要：目的观察多孔钽棒配合股骨头坏死愈胶囊治疗激素性股骨头坏死的临床疗效。方法选择50例激素性股骨头坏死患者(共60髋),按照入组时间随机分为治疗组和对照组,每组各25例(30髋),对照组给予多孔钽棒植入治疗,治疗组在多孔钽棒植入术后配合股骨头坏死愈胶囊口服,5粒/次,3次/日,连续2个月,后2次/日,连续4个月,术后进行随访观察患者患髋Harris评分,评价疗效和股骨头生存时间。结果共有49例(59髋)获得随访,两组患者治疗后髋关节Harris评分较术前明显提高,差异有统计学意义(P<0.01),且治疗组治疗后Harris评分高于对照组,临床疗效及股骨头生存时间均优于对照组,差异有统计学意义(P<0.05)。结论多孔钽棒配合股骨头坏死愈胶囊治疗激素性股骨头坏死疗效较好,能显著改善患髋功能,延长股骨头生存时间。Objective To observe the curative effect of porous tantalum rod and Gugutou Huaisiyu Capsule（GHC）for steroid-induced osteonecrosis of femoral head（SONFH）.Methods A total 60 hips of 50 SONFH patients were randomly assigned to the treatment group and the control group according to grouping time,25 in each group（30 hips）.Patients in the control group were implanted with porous tantalum rod,while those in the treatment group additionally took GHC（5 pills each time,three time per day for 2successive months;and then twice per day for 4successive months）.Then all patients were followed-up to observe Harris hip score.The curative effect and the femoral head survival time were assessed.Results A total of 49 patients（59hips）were followed-up.The Harris hip score of the two groups at the final follow-up was significantly improved after treatment,with statistical difference when compared with before treatment（P〈0.01）.Besides,it was higher in the treatment group than in the control group.The curative effect and the survival time were superior in the treatment group,with statistical difference when compared with the control group（P〈0.05）.Conclusions Porous tantalum rod combined GHC got better effect in treating SONFH.It could significantly improve the function of affected hips and prolong the survival time of femoral head.

关 键 词：多孔钽棒 股骨头坏死愈胶囊 激素性股骨头坏死 

分 类 号：R681.8[医药卫生—骨科学]