2010-2014年江阴市重症手足口病流行特征及其危险因素分析  

Epidemiological characteristics and risk factors of severe cases of hand,foot and mouth disease in Jiangyin, 2010-2014

作　　者：束方燕[1] 钱程[1] 马焰[1] 汤玲[1] 石平[2] 

机构地区：[1]江阴市疾病预防控制中心,江苏江阴214431 [2]无锡市疾病预防控制中心,江苏无锡214023

出　　处：《现代预防医学》2016年第1期15-17,31,共4页Modern Preventive Medicine

基　　金：江苏省预防医学科研项目(Y2015006)

摘　　要：目的分析2010-2014年江阴市重症手足口病的流行特征,探讨手足口病重症的危险因素,为江阴市手足口病的防控工作提供理论依据。方法收集2010-2014年江阴市重症手足口病的相关数据进行描述性分析,同时采用Logistic回归分析重症手足病发病相关危险因素。结果 2010-2014年江阴市共报告手足口病14 291例,重症370例,死亡2例。重症手足口病的发病高峰为5-7月且流动人口聚集的乡镇发病较多,职业以散居儿童和幼托儿童为主,男女性别比为1.64∶1。多因素Logistic回归分析显示流动人口、白细胞升高和出现神经系统症状是患重症手足口病的危险因素,其OR值分别为2.99（95%CI：1.28-7.00）、1.51（95%CI：1.19-1.91）和4.72（95%CI：2.00-11.10）。结论做好流动儿童手足口病的健康宣教,医疗机构针对性的加强手足口病患儿的早期监测,可以有效预防手足口病重症的发生。Objective To explore the epidemiological characteristics and risk factors of hand, food and mouth disease（HFMD） in Jiangyin to provide a scientific basis for controlling and preventing the disease. Methods Descriptive epidemiological analysis was conducted to the severe cases of HFMD in Jiangyin of 2010-2014, and logistic regression was employed to identify the related risk factors. Results A total of 14291 HFMD Cases were reported in Jiangyin during 2010-2014, with 370 severe cases and 2 deaths.The reported eruption of severe HFMD cases was from May to July. The regional distribution is mainly in the towns with concentrated floating population. Children living scattered in kindergartens were most frequently involved and the male/female incidence ratio was 1.64：1. The risk factors were primaily migrant population（OR=2.99, 95%CI： 1.28-7.00）, higher number of white blood cell（OR=1.51, 95% CI： 1.19-1.91） and symptom of nervous system（OR=4.72, 95% CI： 2.00-11.10）. Conclusion Purposefully strengthening the health propaganda for migrant children with HFMD and the early detection of children with HFMD could effectively prevent the occurrence of severe HFMD.

关 键 词：手足口病 重症病例 流行特征 危险因素 

分 类 号：R181.23[医药卫生—流行病学]