血清甘油三酯与冠心病痰瘀证候相关性的Meta分析  

Mata-Analysis on Relationship Between Serum Triglyceride and Coronary Heart Disease of Phlegm and Blood Stasis Syndrome

作　　者：喻松仁[1] 程绍民[1] 周丽[1] 丁成华[1] 袁肇凯[2] 

机构地区：[1]江西中医药大学,江西南昌330004 [2]湖南中医药大学,湖南长沙410007

出　　处：《中华中医药学刊》2016年第1期17-19,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(81273670);重点学科青年教师培养计划项目(2013jzzdxk016)

摘　　要：目的：探讨血清甘油三酯（TG）的异常改变与冠心病（CHD）痰瘀证侯的相关性。方法：应用Meta分析法对相关文献资料中CHD＂痰浊证＂、＂血瘀证＂患者与＂正常对照者＂的TG值进行综合分析。结果：TG值血瘀证比正常对照组高2.334～5.048倍标准差,Total合并=1.02,Total合并95%置信区间为0.27～1.76;痰浊证比正常对照组高2.732～6.73倍标准差,Total合并=1.41,Total合并95%置信区间为0.64～2.18;痰浊证组比血瘀证组高1.069～2.401倍标准差,Total合并=0.48,Total合并95%置信区间为-0.07～1.03。结论：CHD患者血瘀证和痰浊证TG值与正常对照者比较存在显著差异,痰浊证和血瘀证间比较TG值虽无显著性差异,但总体趋势上痰浊证的TG值高于血瘀证,TG的异常改变与CHD痰瘀证候呈密切的相关性。Objective： This study was aimed to investigate the relationship between serum triglyceride（ TG） and coronary heart disease（ CHD） of phlegm and blood stasis syndrome. Methods： Meta- analysis was used on the comprehensive analysis of TG content of CHD patients with phlegm- turbid syndrome,blood- stasis syndrome and normal comparison in related literature. Results： The content of TG was 2. 334 ～ 5. 048 times higher standard deviation in blood stasis syndrome patients than that in the normal comparison group,total merger = 1. 02,95% of total merger of confidence intervals was0. 27 ～ 1. 76. The content of TG was 2. 732 ～ 6. 73 times higher standard deviation in phlegm- turbid syndrome than that in the normal comparison group,total merger = 1. 41,95% of total merger of confidence intervals was 0. 64 ～ 2. 18. The content of TG was 1. 069 ～ 2. 401 times higher standard deviation in phlegm- turbid syndrome group than that in blood stasis syndrome group,total merger = 0. 48,95% of total merger of confidence intervals was- 0. 07 ～ 1. 03. Conclusion：There are significant variations of TG content in CHD patients with blood- stasis and phlegm- turbid syndromes compared to nomal comparison. Although there are no significant variations of TG content between blood- stasis and the phlegm- turbid syndromes,the overall trend is the content of TG in phlegm – turbid syndrome was higher than that in blood- stasis syndrome. The abnomal changes of TG content are closly ralated with phlegm – turbid syndrome.

关 键 词：冠心病 证候 血清甘油三酯 META分析 

分 类 号：R541.4[医药卫生—心血管疾病]