真菌在中药活性成分转化中的应用  

Application of Fungi in active ingredients biotransformation of Chinese traditional medicine

作　　者：贾丹丹[1] 闵涛玲[1] 胡海峰[1] 

机构地区：[1]中国医药工业研究总院上海医药工业研究院创新药物与制药工艺国家重点实验室,上海200040

出　　处：《世界临床药物》2016年第1期50-53,共4页World Clinical Drug

基　　金：重大新药创制(编号:2014ZX09201001-005-001)

摘　　要：真菌具有种类繁多、易培养和酶系统丰富等优势,在中药活性成分转化中具有重要作用。本文综述真菌生物转化在中药活性成分黄酮类、皂苷类和萜类和生物碱类开发应用中的研究现状,并展望未来真菌与中药结合的前景。Fungi plays an important role in active ingredients biotransformation of Chinese traditional medicine, because it is rich in species, easy to culture and complicated in enzyme system. This review describes the research progress on the fungal biotransformation of active ingredients including flavonoid, saponins, terpene and alkaloids. Fungal biotransformation will significantly promote the development of Chinese traditional medicine.

关 键 词：真菌 中药 活性成分 生物转化 

分 类 号：R379[医药卫生—病原生物学] R93[医药卫生—基础医学]