自体骨移植治疗四肢骨折术后骨不连128例疗效分析  

Therapeutic effects of autogenous bone graft on 128 cases of nonunion after operation of limbs fracture

作　　者：刘琼 钟孝政[2] 

机构地区：[1]重庆市长寿区人民医院骨一科,重庆401220 [2]第三军医大学附属第三医院创伤外科

出　　处：《西南国防医药》2016年第1期25-28,共4页Medical Journal of National Defending Forces in Southwest China

摘　　要：目的探讨自体骨移植治疗四肢骨折内固定术后骨不连的疗效及影响因素。方法对128例四肢骨折内固定术后骨不连患者进行自体骨移植治疗,观察其疗效,并分析影响疗效的因素。结果 128例中,疗效优良率达92.2%,失败10例(7.8%)。感染型骨不连植骨失败率(20.0%)高于萎缩型(3.8%)和肥大型骨不连(4.3%)(P<0.05)。失败组患者年龄显著高于治疗未失败组(P<0.01);失败组中开放性骨折、感染性骨不连、合并糖尿病患者数较未失败组显著增多(P<0.05)。结论自体骨移植治疗四肢骨折内固定术后骨不连的疗效显著;影响疗效的因素包括年龄、骨折类型、骨不连类型及是否合并糖尿病。Objective To explore the therapeutic effects of autogenous bone graft on 128 cases of nonunion after operation of limbs fracture and influencing factors. Methods 128 patients with nonunion after operation of limbs fracture were treated by autogenous bone graft, and their therapeutic effects were observed. The influencing factors of therapeutic effects were analyzed. Results Among the 128 cases, the excellent and good rate of therapeutic effects was 92.2%, and there were 10 cases of failure （7.8%）. The failure rate of nonunion of infection type （20.0%） was higher than that of atrophic type （3.8%） or hypertrophy type （4.3%） （P 〈0.05）. The age of the failed group was older than that of the non-failed group（P 〈 0.01）. The constituent ratio of patients with open fractures, nonunion of infection type, and complicating diabetes in the failed group was more than that in the non-failed group （P 〈 0.05）.Conclusion The autogenous bone graft for the treatment of nonunion after operation of limbs fracture has obvious therapeutic effects. The influencing factors of the curative effects include age, bone fracture type, nonunion type, and complicating diabetes.

关 键 词：四肢 骨折 骨不连 自体骨移植 疗效 影响因素 

分 类 号：R683.4[医药卫生—骨科学]