糖化血红蛋白与急性心肌梗死患者心功能的相关性研究  

作　　者：尹璐[1] 杨向军[1] 

机构地区：[1]苏州大学附属第一医院心血管内科,215006

出　　处：《浙江临床医学》2016年第1期39-40,48,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨糖化血红蛋白（HbAlC）与急性心肌梗死（AMI）患者经皮冠状动脉介入治疗（PCI）术后心功能的相关性方法2014年1月至2015#-6月发病时间〈12h因AMI行PCI的患者77例，根据入院时HbAlc水平分为控制组（A组）43例（HbA1c〈6．5％）和升高组（B组）34例（HbAlc≥6．5％），对比分析两组患者心功能的差异。结果两组糖尿病患者比例、空腹血糖（FPG）、糖化血红蛋白（HbAlC）水平比较，差异有统计学意义（P〈0．01）。随着HbA1c水平升高，EF值越低。HbA1c水平与EF、EDV、EDT显著相关。（r=-0．267，P〈0．05；r=0．313，P〈0．01；r=-0．283，P〈0．05）。结论随着HbA1c水平的升高，AMI患者心功能越差，应重视HbA1c在AMI预后中的作用，早期干预，控制血糖。Objective To investigate the relationship between HbAlc and heart function in patients with acute myocardial infarction （ AMI ） who undergoing percutaneous coronary intervention （ PCI ） . Methods Choose from January 2014 to June 2015, 77 AMI patients undergoing PCI were enrolled in this study. According to the level of HbA1c, the patients were divided into control HbAlc grope （ HbA1c〈6.5% ） and high group （ HbA1c ≥6.5 ） , then the heart function were analyzed. Results The ratio between the two groups, diabetics, FPG, HbAlc levels were significantly different. （ P〈0.05 ） . With the increase of HbA1c levels, the value of EF was lower. HbA1c levels and EF, EDV, EDT were significantly correlated. （ r=-0.267, P〈0.05; r=0.313, P〈0.01 ; r=-0.283, P〈0.05 ） .Conclusion With the increase of HbAlc levels, heart function in AMI patients with PCI were worse.HbA1c may be a useful indicator for the early intervention of AMI and blood sugar control.

关 键 词：急性心肌梗死 冠脉成形术 糖化血红蛋白 糖基化 心功能 

分 类 号：R473.5[医药卫生—护理学]