11096例体检者幽门螺杆菌感染现状分析  

Pylori infection distribution in 11 096 individuals

作　　者：李萌辉[1] 张弛[1] 梁晓峰[1] 李世霞[1] 刘俊田[1] 

机构地区：[1]天津医科大学肿瘤医院预防医学中心国家肿瘤临床医学研究中心天津市肿瘤防治重点实验室,300060

出　　处：《天津医药》2016年第1期110-113,共4页Tianjin Medical Journal

摘　　要：目的了解天津地区体检人群中幽门螺杆菌（Hp）感染的现状及其分布特征。方法选取2014全年间在我院行Hp检测的11 096例体检者为研究对象,应用快速尿素酶法检测其Hp的感染情况;以体检者的性别、年龄、职业为依据进行分组分析。结果 11 096例体检者Hp总感染率为30.52%（3 386/11 096）,其中男性为34.77%（1 784/5 131）,女性为26.86%（1 602/5 965）,男性高于女性（P〈0.05）;将体检者按照年龄分为19~29岁、30~39岁、40~49岁、50~59岁、60~69岁和70~92岁组,其Hp感染率分别为19.50%（379/1 944）、25.82%（650/2 517）、31.59%（908/2 874）、37.48%（915/2 441）、41.09%（353/859）和39.18%（181/462）,其中50~59岁、60~69岁和70~92岁组〉40~49岁组〉30~39岁组〉19~29岁组（P〈0.003）;根据体检者职业不同进行分组研究,在医务工作者、工人、教师、工程师、职员、公务员、其他等7个组中Hp感染率分别为25.42%（586/2 305）、29.35%（1 062/3 618）、30.61%（360/1 176）、32.49%（116/357）、33.44%（205/613）、34.52%（455/1 318）和35.23%（602/1 709）,医务工作者Hp感染阳性率25.42（586/2 305）低于工人、教师、职员、公务员和其他人员各组（P〈0.002）。结论应加强中老年尤其是男性的Hp诊疗管理,普及Hp感染预防相关医学知识,从而更有效地预防Hp感染相关疾病的发生。Objective To investigate the distribution of Helicobacter pylori （Hp） infections among general population in Tianjin. Methods Individuals （n=ll 096） who visited our hospital for medical examination and H. Pylori infection screen were included in the research objects. Rapid urease method was utilized to rapidly detect H. pylori infection among the popuhion. Individuals were grouped based on their gender, age and occupations, and then were analyzed. Results H. pylori-positive rate was 30.52% （3 386/11 096） in 11 096 individuals, in which there were 34.77% （1 784/5 131） male and 26.86% （1 602/5 965） female respectively. Individuals were divided into 5 groups according to their ages： 19 to 29 years old group, 30 to 39 years old group, 40 to 49 years old group, 50 to 59 years old group, 60 to 69 years old group and 70 to 92 years old group. The positive rates of H. pylori increased with age： 19.50% （ 379/1 944 ） in 19-29 years old group, 25.82% （650/2 517 ） in 30-39 years old group, 31.59% （ 908/2 874 ） in 40-49 years old group, 37.48% （915/2 441 ） in 50-59 years old group, 41.09% （ 353/859 ） in 60-69 years old group and 39.18% （181/462） in 70-92 years old group. The differences in positive rates between different age groups were all of statistically significant （P 〈 0.05）. Individuals were also divided into seven groups according to their occupations： medical worker group, worker group, teacher group, engineer group, clerk group, civil worker group and other career group. The positive rates of H. pylori infection were 25.42%（586/2 305）, 29.35% （1 062/3 618）, 30.61%（360/1 176）, 32.49%（116/357）, 33.44%（205/613）, 34.52%（455/1 318）and 35.23%（602/1 709） respectively. The positive rate was 25.42% （586/2 305） medical workers, which was lower than that of other occupation groups with significant difference （P 〈 0.002）. Conclusion Good management of H. pylori diagnosis and treatment in mid- dle age and elderly together with populariz

关 键 词：幽门螺杆菌 感染 分布特征 天津 

分 类 号：R183.9[医药卫生—流行病学]