口服抗栓药物的研究进展  

Research progress of oral antithrombotic drugs

作　　者：龚丽英[1] 袁乐宏 黄洁[1] 郭成贤[1] 况赟 马婉乐 阳国平[1] 李静乐[3] 

机构地区：[1]中南大学湘雅三医院临床药理中心,长沙410013 [2]中南大学湘雅三医院急诊科,长沙410013 [3]中南大学湘雅三医院心内科,长沙410013

出　　处：《中国临床药理学杂志》2016年第3期279-282,共4页The Chinese Journal of Clinical Pharmacology

基　　金：国家自然科学基金资助项目(81373476);科技部国际科技合作与交流专项(2014DFA30900)

摘　　要：抗栓治疗在预防和治疗血栓栓塞性疾病中发挥着举足轻重的作用。抗栓药物包括抗凝药物、抗血小板聚集药物和溶栓药物。本文对常见的口服抗栓药物的药理学特征以及研究进展做一综述,旨在指导临床上抗栓药物的安全、合理使用。Antithrombotic drugs play an important role in the prevention and treatment of thromboembolism, which include anticoagulant, anti- platelet therapies and thrombolytic drugs. In this paper, we review the pharmacological properties of these most commonly used oral antithrom- botic drugs and explore the development of anticoagulant and antiplatelet therapies, in order to guide the safety and rational use of antithrombotic drugs in clinic.

关 键 词：抗栓药物 抗凝药物 抗血小板聚集药物 溶栓药物 

分 类 号：R973.2[医药卫生—药品]