表面改性聚丙烯的血液相容性研究进展  

Research Progress in Hemocompatibility of Surface Modified Polypropylene

作　　者：蔡冰[1] 胡跃鑫[1] 韩向艳[1] 雷良才[1] 

机构地区：[1]辽宁石油化工大学化学化工与环境学部,抚顺113001

出　　处：《高分子通报》2016年第1期31-38,共8页Polymer Bulletin

摘　　要：聚丙烯具有价格低廉、无毒、易于加工等优点,使其在许多领域得到广泛的应用。但是聚丙烯自身有较强的疏水性,与血液相接触时,血浆蛋白会在材料表面大量吸附,诱发血小板的粘附和聚集,从而造成凝血和溶血的发生。在生物医用材料的应用过程中,血液相容性是限制材料能否长期应用的关键因素。本文综述了表面改性法提高聚丙烯血液相容性的研究现状、表面改性方法和常用的大分子单体,并分析了当前聚丙烯表面改性研究存在的问题,展望了具有良好血液相容性聚丙烯的发展前景。Polypropylene （PP） is one of the widely used materials in medical apparatus and instruments, owing to its inexpensive, non-toxic and excellent mechanical properties. When hydrophobic polypropylene is exposed to blood, plasma proteins are adsorbed to the surface, and then surface-induced platelet adhesion, subsequent thrombus and hemolysis occur. Hemocompatibility is one of major problems that limit the long period application of biomedical materials. In this paper, the recent progress of the surface modification of polypropylene, the methods and monomers to improve hemocompatibility are reviewed. Meanwhile, limitation of the modification and the prospect of polypropylene with hemocompatibility were presented.

关 键 词：血液相容性 聚丙烯 表面改性 生物医用高分子材料 

分 类 号：TQ325.14[化学工程—合成树脂塑料工业]