极谱法检测碳酸锂药片中锂  

Detection of lithium in lithium carbonate tables by plolargraphy

作　　者：高娅玲[1,2] 王铒[1,2] 孙雪梅 吉喆[1,2] 周会[1,2] 陈文[1,2] 

机构地区：[1]成都理工大学材料与化学化工学院,成都610059 [2]四川省矿产资源化学高校重点实验室,成都610059

出　　处：《分析试验室》2016年第1期107-111,共5页Chinese Journal of Analysis Laboratory

摘　　要：Li^＋在p H 10.5 B-R缓冲溶液中能抑制钙指示剂和H2O2形成络合物,1.0×10^-4mol/L钙指示剂和1.2%的H2O2在0.16 mol/L的B-R缓冲溶液中,于起始电位-0.0 V（vs.SCE）,峰电位（Ep）-0.628V（vs.SCE）处产生一灵敏的极谱还原波,Li^＋能与H2O2和钙指示剂结合使络合物的峰电流下降,该波的二阶导数峰电流（Ip＂）与Li^＋质量浓度在0.8-800μg/m L范围内呈良好的线性关系,检出限为0.3146μg/m L。回收率为94.4%-102.9%。方法已用于碳酸锂片中Li＋的测定,并讨论了其机理。电极反应物是钙指示剂和H2O2的络合物。A method for determination of Li^＋ established. It＇s based on the inhibitory effect of lithium carbonate indirectly by polargraphic analysis has been of Li^＋ on the peak current of complex forming by Calcium indicator and H2O2, in the B-R buffer solution of pH 10. 5. The optimal determination conditions are 4. 0 × 10^-4 mol/L Calcium indicator, 1.2% H2O2, and 0. 16 mol/L B-R buffer solution （ pH 10. 5 ）. The starting potential is 0 V （vs. SCE） and the peak potential is-0.628 V （vs. SCE） by JP-303 pol linearly proportional to the concentration of Li^＋ over the range of 0. 8 - 800 μg/mL, and the detection limit is 0. 3146μg/mL. The recoveries of samples are from 94. 4% to 102. 9%. The method is simple, rapid and accurate. The result is satisfactory when it is used to analyze Li^＋ of lithium carbonate tables. It was proved by polarogrophy that the electro-active complex was complex formed by Calcium indicator and H2O2. A brief discussion of the electrode reaction was also given.

关 键 词：碳酸锂药片 锂 极谱法 

分 类 号：R917[医药卫生—药物分析学]