雷公藤多苷联合米诺环素治疗玫瑰痤疮23例临床观察  

Clinical Observation of Tripterygium Wilfordii Polyglycoside Combined with Minocycline in the Treatment of 23 Cases with Acne Rosacea

作　　者：李玉湘[1] 傅强[1] 张秀春[1] 杜丽霞[1] 

机构地区：[1]青海红十字医院皮肤科,青海西宁810000

出　　处：《中国皮肤性病学杂志》2016年第2期214-215,218,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的评价雷公藤多苷联合米诺环素治疗红斑、丘疹脓疱期玫瑰痤疮的临床疗效和安全性。方法入选的45例玫瑰痤疮患者通过随机数字表法随机分为两组,治疗组(23例)予口服雷公藤多苷及米诺环素,对照组(22例)仅予口服米诺环素,疗程均为6周。结果治疗结束时,治疗组有效率82.61%,对照组有效率50.00%,差异有统计学意义(P<0.05)。治疗过程中均未出现严重不良反应。结论雷公藤多苷联合米诺环素治疗玫瑰痤疮安全而有效。Objective To evaluate the efficacy and safety of tripterygium wilfordii polyglycoside combined with minocycline in the patients with erythema and papulopustular ache rosacea. Methods Forty-five cases of patients with ache rosacea in accordance ruth the random number table were divided into two groups. Twenty-three cases of treatment group were treated with tripterygium wilfordii polyglycoside combined with minocycline,while 22 cases of control group were treated with minocycline. The effects were observated for 6 weeks. Results The response rates were 82. 61% and 50. 00% respectively. There was significant difference between the treatment group and the control group （ P 〈0. 05 ）. Conclusion Tripterygium wilfordii polyglycoside combined with minocycline for acne rosaeea is safe and effective.

关 键 词：雷公藤多苷 米诺环素 玫瑰痤疮 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]