益气清热化湿法治疗脓毒症胃肠功能障碍的临床研究  

Clinical Study of Yiqi Qingre Huashi Method in the Treatment of Gastrointestinal Dysfunction in Sepsis Type of Dampness and Heat in Spleen

作　　者：王珊珊[1] 赵浩[2] 孔立[2] 李泉 

机构地区：[1]山东中医药大学,山东济南250014 [2]山东中医药大学附属医院,山东济南250014 [3]江苏省宿迁市第一人民医院,江苏宿迁223800

出　　处：《中国中医急症》2016年第1期20-21,105,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：山东省自然科学基金计划项目(ZR2010HL062)

摘　　要：目的观察益气清热化湿法对脓毒症湿热蕴脾型胃肠功能障碍的临床疗效。方法将60例脓毒症胃肠功能障碍患者随机分为治疗组和对照组两组各30例。对照组予西医常规治疗,治疗组在对照组基础上加益气温胆汤治疗。疗程均为7 d。观察比较两组治疗前后进行胃肠功能障碍评分、APACHEⅡ评分、中医证候积分及C反应蛋白(CRP)、降钙素原(PCT)、白细胞计数(WBC)、中性细胞比率(NEU%)值的变化。结果两组治疗前胃肠功能障碍评分、APACHEⅡ评分、中医证候积分、CRP、PCT、WBC、NEU%值差别不大(均P>0.05)。治疗后两组胃肠功能障碍评分、APACHEⅡ评分、中医证候积分、CRP、PCT、WBC、NEU%值均较治疗前下降(均P<0.01),且治疗组改善优于对照组(均P<0.01)。结论益气清热化湿法治疗脓毒症湿热蕴脾型胃肠功能障碍疗效显著。Objective： To observe the clinical effect of Yiqi Qingre Huashi method on gastrointestinal dysfunction in sepsis type of dampness and heat in spleen. Methods： 60 patients were randomly divided into two groups,30 cases in the treatment group for the routine treatment of Western medicine plus Yiqi Wendan Tang,the control group routine treatment of Western medicine. The treatment course lasted for 7 days. Before and after treatment,gastrointestinal dysfunction was scored,and APACHE score and C reactive protein（CRP） were detected and compared. Results： Two groups of gastrointestinal dysfunction score,APACHE score and CRP valuedecreased significantly compared with before treatment（P〈0.05）, compared with the control group,the treatment group decreased significantly（P〈0.05）,the treatment group than the control group（P〈 0.05）. Conclusion： The curative effect of Yiqi Qingre Huashi method on gastrointestinal dysfunction in sepsis type of dampness and heat in spleen is obvious.

关 键 词：脓毒症胃肠功能障碍 湿热蕴脾 益气清热化湿法 

分 类 号：R631[医药卫生—外科学]