益气养阴不同方药治疗快速性室性早搏气阴两虚证的系统评价  

Systematic Review of Different Formulas for Reinforcing Qi and Nourishing Yin on Treating Tachyarrhythmia with Deficiency of Both Qi and Yin Syndrome

作　　者：王凤[1] 徐华英[1] 杜文婷[1] 章怡祎[1] 张娜[1] 刘萍[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《中国中医急症》2016年第1期54-57,75,共5页Journal of Emergency in Traditional Chinese Medicine

基　　金：上海市三年行动计划(ZY3-CCCX-3-3039)

摘　　要：目的评价益气养阴不同方药治疗快速性室性早搏气阴两虚证的疗效。方法全面搜集有关益气养阴不同方药治疗快速性室性早搏气阴两虚证的随机对照试验,筛选合格研究,应用Jadad评分法进行质量评价,运用Meta分析方法统计比较相关数据。结果 6项研究被纳入6种药物的系统评价;Jadad评分结果显示1篇文章得3分,属高质量文献,其余为1分,属低质量文献;6项研究分别采用临床总有效率、中医临床症状改善、室性早搏疗效有效率和室性早搏数量变化中的两项或1项指标进行了疗效比较;Meta分析结果显示茱萸颗粒、扶正和脉饮、生脉四物汤、生脉宁心汤、通脉养心丸、安神伏脉汤对快速性室性早搏气阴两虚证的中医临床症状改善、早搏数量减少等方面均有效。结论益气养阴不同方药治疗快速性室性早搏气阴两虚证有一定的疗效,而由于纳入研究的各方药缺乏足够的临床试验,故无法进一步筛选比较茱萸颗粒、扶正和脉饮、生脉四物汤、生脉宁心汤、通脉养心丸、安神伏脉汤疗效的优劣。要进一步验证益气养阴不同方药治疗快速性室性早搏气阴两虚证的疗效,尚需进行设计合理、执行严格、多中心大样本的随机对照试验。Objective： To evaluate different formulas for reinforcing qi and nourishing yin（or Yi Qi Yang Yin Fang YQYYF） on treating tachyarrhythmia with deficiency of both qi and yin syndrome. Methods： Randomized controlled trials（RCTs） of YQYY in treating tachyarrhythmia were collected. Inclusion/exclusion,data extraction and validity assessment were carried out independently. Jadad scale was used to make quality evaluation. Related data were analyzed and compared with Meta-analysis. Results： Total 6 RCTs including 6 formulas were analyzed by systematic review. An article assessed by Jadad scale getting 3 points was classified to high-quality articles,and others getting 1 point was classified to low-quality articles. Total clinical curative effect and one or two in-dexes of clinical symptoms were selected as the standards to compare efficacy of each study. Meta-analysis showed that Zhuyu Keli,Fuzheng Hemai Yin,Shengmai Siwu Tang,Shengmai Ningxin Tang,Tongmai Yangxin Wan and Anshen Fumai Tang were effective on treating tachyarrhythmia and improving clinical symptoms. Conclusion： YQYY is effective on treating tachyarrhythmia with deficiency of both qi and yin syndrome. But the effects of Zhuyu Keli,Fuzheng Hemai Yin,Shengmai Siwu Tang,Shengmai Ningxin Tang,Tongmai Yangxin Wan and Anshen Fumai Tang can not be compared. More rationally designed and strictly executed RCTs with large samples are necessary.

关 键 词：气阴两虚证 快速性室性早搏 益气养阴 系统评价 

分 类 号：R541.73[医药卫生—心血管疾病]