致赤大袋鼠皮肤化脓的荚膜血清A型多杀性巴氏杆菌的分离鉴定  

Isolation and identification of a capsular serotype-A Pasteurella multocida that caused suppuration in Macropus rufus

作　　者：周伟[1,2] 李沐[1,2] 王海军 祝令伟[1,2] 孙洋[1,2] 郭学军[1,2] 

机构地区：[1]军事医学科学院军事兽医研究所 [2]吉林省人兽共患病预防与控制重点实验室,长春130122 [3]吉林省野生动物救护繁育中心,长春130122

出　　处：《兽类学报》2016年第1期123-128,共6页Acta Theriologica Sinica

基　　金：国家"863"项目(2012AA022006)

摘　　要：多杀性巴氏杆菌（Pasteurella multocida）是巴氏杆菌属的成员之一,能感染鸡、鸭、兔、猪和牛等多种家养动物和部分野生动物,不同动物感染后的疾病命名不同,如禽霍乱（Eveleth et al.,1949）、猪肺疫和牛出血性败血症（陆承平,2001）。该菌为革兰氏阴性球杆菌或短杆菌,新分离菌株瑞氏染色两极着色明显,To find out the etiological cause of pyogenic infection of two Macropus rufus,three samples from the pus of the infected sites were collected and subject to microbiological examinations. A strain of gram-negative bacteria was isolated. Based on the results of the morphological and biochemical tests,multiple genes sequence analyses and ERIC-PCR fingerprints,the isolate was identified as a capsular serotype-A Pasteurella multocida and was then named as PM- 1. PM- 1was lethal to mice with an median lethal dose（ LD50） at 1. 99 × 10^2 cfu / mice. It was found to be sensitive to levofloxacin and ciprofloxacin. Treatment with levofloxacin hydrochloride ointment therefore cured the infected sites in the animals and the spread of the disease was then under the control.

关 键 词：赤大袋鼠 多杀性巴氏杆菌 荚膜血清A型 

分 类 号：Q95-339[生物学—动物学]