机械灌注保存供体心脏研究进展  

Research Progress of Machine Perfusion for Donor Heart Preservation

作　　者：李勇男[1,2] 吉冰洋[2] 高秉仁[1] 

机构地区：[1]兰州大学第二临床医学院兰州大学第二医院,兰州市730000 [2]北京协和医学院中国医学科学院国家心血管病中心阜外医院心血管病国家重点实验室,北京市100037

出　　处：《中国分子心脏病学杂志》2015年第6期1550-1553,共4页Molecular Cardiology of China

摘　　要：心脏移植是治疗终末期心脏病的有效外科手段。临床实践中,使用心脏保存液保存供体心脏,但其仅有4-6小时的安全保存时间。机械灌注保存供体心脏的出现,可以提高供体心脏保存效果与延长保存时间。本文就机械灌注保存供体心脏的现状与研究进展作一综述。Heart transplantation has been widely accepted as an effective treatment for end-stage heart diseases. Currently, the most commonly used method of preservation for transplantation is static cold storage, however, donor heart preservation is limited to 4 to 6 hours of cold ischemia storage. Machine perfusion has been proposed as a system that provides a continuous perfusion of oxygenated blood or preservation solution to increase the number and quality of donor heart available for transplant. In this paper, we summarize the status and research progress of machine perfuison for donor heart preservation.

关 键 词：心脏移植 心肌保护 机械灌注保存 

分 类 号：R654.2[医药卫生—外科学]