院内侵袭性肺部烟曲霉菌感染临床分析  

Clinical analysis of invasive pulmonary Aspergillus fumigatus infection in hospital

作　　者：王婷[1] 刘晓民[1] 吕和[1] 

机构地区：[1]哈尔滨医科大学附属第一医院呼吸内科,黑龙江哈尔滨150001

出　　处：《哈尔滨医科大学学报》2015年第6期537-538,542,共3页Journal of Harbin Medical University

摘　　要：目的分析哈尔滨医科大学附属第一医院侵袭性肺部烟曲霉菌感染患者的临床资料、流行病学趋势及预后。方法选取临床诊断患者痰液作为标本。回顾性分析其基本信息、应用抗菌药物、侵入性操作及预后等情况。结果患者平均年龄为(65.04±4.76)岁;呼吸科患者占比例为37.23%;约80%以上的患者曾应用广谱抗生素,60%的患者曾应用糖皮质激素,42%的患者曾留置尿管,34%行吸痰操作;死亡率为22.34%。结论烟曲霉菌在痰中分离最多,老年患者多见,主要集中在呼吸科与ICU;及时有效的抗真菌治疗可降低患者死亡率,提高治愈率。Objective To analyze clinical datas, epidemiological trends and prognosis of inva- sire pulmonary AspergiUus fumigatus-infected patients in the First Affiliated Hospital of Harbin Medical University. Methods The surveyed finalists were those who were clinically diagnosed patients, and samples were selected from sputum. The basic information, the use of antimicro- bial drugs, invasive procedures and prognosis, etc were analyzed retrospectivly. Results The average age of the patients was （65.04 _＋ 4.76 ） years old ; respiratory patients accounted for 37.23% proportion; more than 80% of patients had used broad-spectrum antibiotics, 60% of patients had used corticosteroids, 42% of patients had indwelled catheter, 34% had suction operation ; mortality rate was 22.34%. Conclusion Aspergillus fumigatus isolated in sputum most common in elderly patients, mainly in the respiratory department and ICU; timely and ef- fective antifungal therapy may reduce mortality and improve the cure rate.

关 键 词：侵袭性 烟曲霉菌 感染 分析 

分 类 号：R519.8[医药卫生—内科学]