静脉留置针肝素封管与肝素诱导性血小板减少症的相关性研究  

The relative of Venous remaining needle Heparin Sealing and Heparin induced Thrombocytopenia

作　　者：李淑珍 陈爱兰 刘云 赵茜 蒋玉敏 

机构地区：[1]山东省阳谷县人民医院,阳谷县252300

出　　处：《当代护士（中旬刊）》2016年第2期25-27,共3页Modern Nurse

摘　　要：目的观察静脉留置针肝素封管与肝素诱导性血小板减少症的关系。方法观察2013年10月1日~2014年10月1日在本院住院、应用静脉留置针肝素封管的成年患者,在第5天、第10天进行血小板的监测,发现肝素诱导性血小板减少症患者,并观察其临床特征及预后。结果共纳入2142例患者,其中肝素/血小板因子4抗体阳性者119例,占5.56%,其中发生HIT16例,发生率0.747%,其中男9例,女7例,平均年龄（61±7）岁,发生出血事件者6例,占37.5%,发生血栓形成者2例,占12.5%,血栓形成患者同时合并出血。经治疗后无死亡及出现后遗症,下肢静脉血栓形成患者10d后血栓消失。结论静脉留置针肝素封管可引起肝素诱导性血小板减少症发生,及时发现并给予合理的处理患者的预后良好。Objective To investigate the relative of venous remaining needle heparin sealing and heparin induced thrombocytopenia. Meth- ods To observe the adult patients using venous remaining needle heparin sealing. The count of PLT and antibody of heparin/PF4 was exam- ined in the 5,10 day. To find the heparin induced thrombocytopenia patients, and observe the clinical features. Results 119 of the 2142 patents were found HIT antibody, the incidence rate is.5.56%, and 16 patients were diagnosed HIT, the incidence rate is 0. 747% , male were 9, the age from 21 to 78 year, the average age is 61 ± 7. The patients with hemorrhage were 6 （ 37.5% ） and the thrombosis were 2 （ 12.5% ）. The platelet count return to normal in fourth to tenth days and without death and sequel. The thrombus disappeared in the tenth day. Conclusion venous remaining needle heparin sealing can reduce heparin induce thrombocytopenia, the patients can recover well if they can be found in timely and received reasonable remedy.

关 键 词：静脉留置针 肝素 肝素诱导性血小板减少症 

分 类 号：R473.5[医药卫生—护理学]