江苏省东台市农村地区散发戊型病毒性肝炎流行病学特征分析  

Epidemiological characteristics of sporadic hepatitis E in the rural area of Dongtai,Jiangsu Province,China

作　　者：姜汉民[1] 王一军[1] 张雪峰[2] 王忠泽[1] 杨昌林[1] 蔡加平[1] 闫强[3] 吴婷[3] 张军[3] 朱凤才[2] 夏宁邵[3] 黄守杰[3] 

机构地区：[1]江苏省东台市疾病预防控制中心,东台224200 [2]江苏省疾病预防控制中心,南京210009 [3]分子疫苗学与分子诊断学国家重点实验室,国家传染病诊断试剂与疫苗工程技术研究中心,厦门大学公共卫生学院,厦门361102

出　　处：《中国人兽共患病学报》2016年第1期95-98,共4页Chinese Journal of Zoonoses

基　　金：国家自然科学基金项目(81373061);江苏省科技支撑计划(社会发展)项目(BE2013723)资助~~

摘　　要：目的分析2008-2011年江苏省某农村地区戊型病毒性肝炎流行病学特征。方法利用已建立的疑似肝炎症状监测系统主动发现戊型病毒性肝炎患者,并对其流行病学特征进行分析。结果 2008-2011年戊型肝炎所占急性病毒性肝炎比例为27.29%,成为第2个主要病毒性肝炎。戊型肝炎年平均发病率2.2/万,戊肝发病全年散发,冬春季节高发;男性发病率高于女性,发病率随年龄增长逐渐升高,发病平均年龄(55.48±14.32)岁。戊型肝炎病毒株HEV1、4型并存,以HEV4型为主(95.6%)。结论本地戊肝呈散发,中老年高发,男性多于女性,以HEV4型为主。In order to analyze the epidemiologic characteristics of hepatitis E in the rural area of Jiangsu Province during the period of 2008-2011, an established monitoring system of suspected hepatitis was used to detect patients of hepatitis E. The study showed that hepatitis E cases accounted for 27.29~ of the total acute hepatitis cases during this period, which indicated hepatitis E had become the second major hepatitis in the rural area of Jiangsu Province. The average annual incidence rate of hepatitis E was around 0.22%o. Hepatitis E was sporadic throughout the whole year, with a higher incidence in spring and winter. The morbidity of hepatitis E was higher in men than that in women and was rising with age. The average age of all cases is 55.48±14.32 years. The research also revealed that HEV of genotype 4 was the major genotype in the rural area of Jiangsu Province which accounted for 95.6%, while the proportion of genotype 1 was 4.4%. In conclusion, hepatitis E in the rural area of Jiangsu Province is sporadic throughout the whole year, and HEV of genotype 4 is the major genotype. The incidence of hepatitis E is higher in the middle-aged and old people and it is higher in men than that in women.

关 键 词：戊型病毒性肝炎 流行特征 疾病控制 

分 类 号：R183.4[医药卫生—流行病学]