氟哌啶醇联合血液灌流在维持性血液透析患者并发兴奋性精神异常治疗中的临床应用  

Clinical Application of Haloperidol Combined with Hemoperfusion in the Treatment of Maintenance Hemodialysis Patients with Excited Mental Disorders

作　　者：刘德慧[1] 钟静静[1] 陈江林[1] 杨光[1] 任称发[1] 方卫东[1] 

机构地区：[1]江西省赣州市人民医院,江西赣州341000

出　　处：《中国医学创新》2015年第33期56-58,共3页Medical Innovation of China

基　　金：2011年江西省卫生厅科研计划课题(2011A092)

摘　　要：目的:探讨氟哌啶醇联合血液灌流对维持性血液透析患者并发兴奋性精神异常治疗的价值。方法:选取2012年5月-2014年5月本院收治的维持性血液透析并发兴奋性精神异常患者40例作为治疗组,选择本院同期维性持血液透析患者40例作为对照组,比较其治疗效果。采用随机数字表法将治疗组分为氟哌啶醇组和传统治疗组,两组均给予血液透析及血液灌流,氟哌啶醇组在此基础上给予氟哌啶醇治疗,比较两组临床疗效。结果:治疗组与对照组职业、年龄、透析频次、PTH、CRP、血色素水平及血清白蛋白比较,差异均有统计学意义(P<0.05),氟哌啶醇组治疗24、36、48 h后的精神症状缓解的患者例数多于对照组,比较差异均有统计学意义(P<0.05)。结论:维持性血透并发兴奋性精神异常的发生与患者职业、年龄、透析频次、PTH、CRP、血色素水平及血清白蛋白有关;采用氟哌啶醇联合血液灌流治疗维持性血液透析患者并发兴奋性精神异常的效果显著,可推广应用。Objective：To investigate the value of Haloperidol combined with hemoperfusion in the treatment of maintenance hemodialysis patients with mental disorders.Method：40 maintenance hemodialysis patients with mental disorders in our hospital from May 2012 to May 2014 were selected as the treatment group.40 patients with maintenance hemodialysis in our hospital were selected as the control group at the same time.The treatment group was randomly divided into the Haloperidol group and the traditional therapy group.The treatment group was given maintenance hemodialysis and hemoperfusion.The Haloperidol group was given Haloperidol on the basis of the treatment group.The clinical effects were compared between Haloperidol group and traditional therapy group.Result：The differences in occupation,age,dialysis frequency,PTH,CRP,hemoglobin levels and serum albumin between the treatment group and the control group were statistically significant（P〈0.05）.The numbers of patients with mental symptom remission after 24,36,48 hours of treatment in the Haloperidol group were more than those in the traditional therapy group,the differences were statistically significant（P〈0.05）.Conclusion：The incidence of maintenance hemodialysis patients with mental disorders has correlations with occupation,age,dialysis frequency,PTH,CRP,hemoglobin levels and serum albumin.Haloperidol combined with hemoperfusion in the treatment of maintenance hemodialysis patients with mental disorders has significant effects.It is worthy of promotion.

关 键 词：氟哌啶醇 血液灌流 血液透析 

分 类 号：R459.5[医药卫生—治疗学]