脓毒症患儿血清铁蛋白水平测定的意义及与预后的关系  

The relationship between serum ferritin and prognosis in children with sepsis

作　　者：朱金兰[1] 黄铁栓[1] 

机构地区：[1]广东省深圳市儿童医院,518038

出　　处：《检验医学与临床》2015年第A02期101-103,共3页Laboratory Medicine and Clinic

摘　　要：目的：探讨脓毒症患儿血清铁蛋白水平变化的临床意义。方法选择2013年3月‐2014年9月收治的86例脓毒症患儿作为观察对象，根据病情分为脓毒症组（54例）、严重脓毒症组（32例），以同期普通感染的非脓毒症患儿30例作为对照组。检测入院时及治疗过程中各组血清铁蛋白水平，分析与脓毒症及其病情、预后的相关性。结果脓毒症组、严重脓毒症组与对照组比较，差异均有统计学意义（P ＜0．01），严重脓毒症组与脓毒症组比较，差异有统计学意义（P＜0．01），治疗后病情好转及痊愈患儿，SF 下降或正常，病情加重或死亡患儿，SF 进一步升高。结论血清铁蛋白可作为脓毒症诊断的辅助指标，SF 持续升高患儿预后差。Objective To explore the changes of serum ferritin concentration in children with severe sepsis and their clinical significance .Methods Eighty‐six children with sepsis were enrolled .They were divided into sepsis group （54） and severe sepsis group （32） according to the severity of sepsis .Thirty children with mild infection served as control group .The levels of serum ferritin（SF）were tested and analyzed .Results there were significant differences of the concentration of SF among the groups（P〈0 .01） .The level of SF in sepsis group went down with the improvement as contract to go up in severe sepsis group and dead cases .Conclusion SF has auxiliary value in the diagnosis of sepsis .

关 键 词：儿童 脓毒症 血清铁蛋白 预后 

分 类 号：R392[医药卫生—免疫学]