快速诊断试剂盒在援非人员疟疾诊断中的应用研究  

Study on the application of rapid diagnostic test in the diagnosis of malaria for Africa staff

作　　者：江海龙[1] 田利源[2] 王光辉 常学辉 

机构地区：[1]空军总医院急诊部,北京100036 [2]人口与健康空军总医院平台中心,北京100036 [3]空军临潼疗养院,陕西西安710600 [4]北京空军95865部队卫生队,北京102218

出　　处：《检验医学与临床》2015年第A02期107-108,共2页Laboratory Medicine and Clinic

摘　　要：目的：探讨疟疾快速诊断试剂盒在援非人员中临床运用效果，为临床应用提供参考。方法快速诊断试剂盒与镜检法对98例援非人员疟疾、疑似疟疾进行检测对比分析。结果镜检疟原虫阳性41例（恶性疟疾pf38例，间日疟 Pv2例，卵形疟 Pm1例），阳性率：41．83％；快速诊断试剂盒诊断疟原虫阳性40例（pf38例，Pv ＋Pm2例），阳性率：40．82％；该试剂盒的总灵敏度97．56％，总特异性100％。（Kappa ＝0．487，P＞0．05）。结论疟疾快速诊断试剂盒对非洲恶性疟疾诊断敏感性、特异性均较高，非常适合于镜检技术及条件不足的中国援非人员开展疟疾检测。Objective To explore the implicational effect of rapid diagnostic test in the diagnosis of malaria for Africa staff .Methods 98 African staff suspicious cases of malaria were checked with rapid diagnostic test （RDT ） and microscopy method .Results 41 positive cases were detected by microscopy method （pf38cases ,Pv2cases , Pm1cases）with positive rate of 41 .83% ,and 40positive cases were detected by RDT （pf38cases ,Pv ＋ Pm2cases） with positive rate of 40 .82% .One Po case was not detected by rapid diagnostic test .There was no significant difference between the two methods（Kappa = 0 .487 ,P 〉 0 .05） .The sensitivity of the rapid diagnostic test was 97 .56% ,with the specificity of 100% .Conclusion The sensitivity and specificity of RDT are very high ,it is very good for diagnose malaria in African stuff especially in the place absent of microscopic examination .

关 键 词：疟疾 诊断 快速诊断试剂盒 非洲 

分 类 号：R52[医药卫生—内科学]