老老年高血压患者抑郁状态与动态血压参数相关性研究  

Correlation between Depression and Ambulatory Blood Pressure Parameter of Very Elderly Hypertensive Patients

作　　者：魏艺[1] 胡元会[1] 杨传华[2] 宋庆桥[1] 耿彦婷[1] 郑昭瀛[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]山东中医药大学第一附属医院

出　　处：《医学研究杂志》2016年第1期69-73,共5页Journal of Medical Research

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项基金资助项目(JDZX2012109)

摘　　要：目的研究老老年高血压患者抑郁状态与动态血压监测相关指标之间的关系,为进一步临床诊疗提供更多的依据。方法纳入老老年原发性高血压患者121例,均采集病史、行常规生化检查、24h动态血压监测,根据老年抑郁量表得分情况将其分成正常组58例,为1组;轻度抑郁组32例,为2组;重度抑郁组31例,为3组;比较3组的间动态血压参数的差异。结果老老年高血压抑郁状态与动态血压多参数见存在相关性,经多元线性逐步回归分析显示,24h收缩压负荷与老老年高血压患者抑郁之间的关系最为密切。结论在临床实践中,24h收缩压负荷或许可以成为患者抑郁状态的一个预测指标;进而通过积极的改善患者的抑郁状态,使血压的更加稳定,最终改善患者心脑血管病预后,提高生活质量。Objective To study the relationship between ambulatory blood pressure monitoring （ABPM）parameters and depression of very elderly hypertensive patients and provide more evidence for clinical diagnosis and treatment. Methods The study included 121 very elderly hypertensive patients. We collected medical history, performed routine biochemical examination, and 24 - hour ambulatory blood pressure monitor. All the patients were divided into 2 groups according to the Geriatric Depression Scale scores,with 58 cases in nor- mal group named groupl , 32 cases in mild depression group, as group2, 31 cases in severe depression group, as group3. Ambulatory blood pressure difference was compared between the three groups. Results There was correlation between depression and several parame- ters of ABPM in very elderly hypertensive patients. By multiple linear regression analysis,the results showed that there was relationship between the 24 hours systolic pressure load hypertension in very elderly patients with depression. Conclusion In clinical practice, 24 - hour systolic blood pressure load might be a predictor of depression in patients; thus improving depression positively would help making blood pressure more stable, and ultimately improves the prognosis cardiovascular disease, and quality of life of very elderly pypertensive patients.

关 键 词：老老年 高血压 抑郁状态 动态血压监测 

分 类 号：R544[医药卫生—心血管疾病]