七氟醚和异丙酚复合氯胺酮用于小儿短小手术的临床观察  

Sevoflurane and Propofol Combined with Ketamine in Application of Children' Anesthesia in Small Operations

作　　者：方正春[1] 夏中元[1] 赵博[1] 吴洋[1] 侯家保[1] 

机构地区：[1]武汉大学人民医院麻醉科,430000

出　　处：《医学研究杂志》2016年第1期125-128,共4页Journal of Medical Research

摘　　要：目的评价七氟醚和异丙酚复和氯胺酮在小儿短小手术的临床效果。方法选取笔者医院择期小儿手术70例,随机分为两组(S组:七氟醚复合氯胺酮;P组:异丙酚复合氯胺酮),每组35例。比较两组患儿麻醉过程中平均动脉压(MAP)、心率(HR)、血氧饱和度(Sp O2)等生命体征变化情况,比较两组患儿麻醉诱导时间、苏醒时间、苏醒质量等麻醉效果及术中、术后不良反应发生情况。结果两组患儿麻醉过程中生命体征差异无统计学意义(P>0.05);S组的麻醉诱导时间、苏醒时间均明显短于P组(P<0.05),苏醒质量S组明显高于P组(P<0.05);两组的不良反应差异无统计学意义(P>0.05)。结论两种方法均可以很好地用于小儿短小手术的麻醉,但七氟醚复合氯胺酮麻醉是更为有效的麻醉方式。Objective To evaluate complex of sevoflurane and propofol and ketamine in pediatric short elective surgery. Methods Seventy cases in our hospital for elective pediatric surgery, were randomly divided into two groups： S Group （ sevoflurane combined with ketamine） , P Group （propofol combined with ketamine）. Comparison of the two groups of children with induction time, mean arterial blood pressure before and after surgery （MAP） , heart rate （HR） , oxygen saturation （SpO2 ） changes and postoperative adverse events was performed. Results Anesthesia onset time, recovery time in Group S was significantly shorter than P group（P 〈 0.05）. No significant differences between groups of patients vital signs was found. Adverse reactions in both groups had no significant difference （P 〉 0.05）. Conclusion Sevoflnrane combined with ketamine anesthesia could be used in children undergoing elective surgery as a safe and effective anesthesia methad.

关 键 词：小儿短小手术 七氟醚 异丙酚 氯胺酮 

分 类 号：R614[医药卫生—麻醉学]