瑶药瑞香通养助孕胶囊质量控制研究  

Study on Quality Control Standards of Yao Medicine Ruixiangtongyangzhuyun Capsules

作　　者：梁威[1,2] 刘元[1,2] 宋志钊[1,2] 文志云[1,2] 

机构地区：[1]广西中医药研究院,广西南宁530022 [2]广西中药质量标准研究重点实验室,广西南宁530022

出　　处：《广西科学》2015年第6期627-630,共4页Guangxi Sciences

基　　金：广西科技攻关项目(桂科攻1346008-7);广西卫生厅重点科研课题项目(重S201308-06);广西瑶族习用药材质量评价与标准研究项目(MZY2012025)资助

摘　　要：【目的】建立瑶药瑞香通养助孕胶囊质量标准。【方法】采用TLC法对处方中毛瑞香和地榆进行定性鉴别,并采用HPLC法测定岩白菜素的含量。【结果】毛瑞香和地榆薄层色谱图斑点清晰,重现性好,无干扰;岩白菜素在10.5~168.0μg·mL^(-1)线性良好,r=0.9998,平均回收率为98.9%,RSD为1.23%(n=6)。【结论】建立的质量控制方法可有效控制瑶药瑞香通养助孕胶囊的质量。【Objective】This study was conducted to set up the quality control standards of Yao medicine Ruixiangtongyangzhuyun capsules.【Methods】Daphnes atrocaulis Herbs and garden burnet were identified qualitatively by TLC methods,while bergenin content was determined by HPLC method.【Results】The TLC figures of the two extracts were distinct,reproducible and noninterference.The calibration curves were linear in the range of 10.5~168.0μg·mL^(-1) for bergenin(r=0.9998),average recovery of bergenin was 98.9%.and RSD was 1.23%(n =6).【Conclusion】The quality of Yao medicine Ruixiangtongyangzhuyun capsule can be effectively controlled by these quality standards.

关 键 词：瑞香通养助孕胶囊 瑶药TLC HPLC 岩白菜素 

分 类 号：R286[医药卫生—中药学]