灰毛豆Tephrosia purpurea中查尔酮类化合物的分离鉴定  

Study on Chalcones fromTephrosia purpurea

作　　者：周荷盈[1] 张霞[1] 高银清[1] 何燕[2] 

机构地区：[1]广东省第二人民医院,广东广州510317 [2]增城市人民医院(中山大学附属博济医院),广东广州511300

出　　处：《广西科学》2015年第6期631-636,共6页Guangxi Sciences

摘　　要：【目的】为探讨灰毛豆属植物Tephrosia purpurea化学成分中的查尔酮类化合物,对其枝、叶部位进行化学成分分离及结构解析。【方法】采用乙醇提取、溶剂萃取、柱层析分离方法得到多种灰毛豆属T.purpurea化学成分,并用波谱分析手段对其进行结构表征。【结果】从灰毛豆属T.purpurea中共分离鉴定出11个查尔酮类化合物,分别为elatadihydrochalcone(1),spinochalcone A(2),3′,5′-diisopentenyl-2′,4′-dihydroxychalcone(3),candidachalcone(4),O-methylpongamol(5),(+)-tephrosone(6),spinochalcone C(7),epoxyobovatachalcone(8),tunicatachalcone(9),crassichalone(10),(S)-elatadihydrochalcone(11)。【结论】以上化合物均为查尔酮,且均属首次从该植物中分离得到。【Objective】There is a rich resource of Tephrosia purpureain China.The chemical components from different parts of T.purpureawere investigated in order to explore their structures.【Methods】The chalcones were isolated and purified by column chromatography on silica gel,and their structures were identified by spectral analyses and compared with literature.【Results】Eleven chalcones chemical components were obtained from the branches and leaves of T.purpurea and characterized as:elatadihydrochalcone(1),spinochalcone A(2),3′,5′-diisopentenyl-2′,4′-dihydroxychalcone(3),candidachalcone(4),O-methylpongamol(5),(+)-tephrosone(6),spinochalcone C(7),epoxyobovatachalcone(8),tunicatachalcone(9),crassichalone(10)and(S)-elatadihydrochalcone(11).【Conclusion】All the compounds mentioned above belong to chalcones,which are isolated fromT.purpureafor the first time.

关 键 词：灰毛豆 查尔酮类化合物 分离 结构鉴定 

分 类 号：O631[理学—高分子化学]