急性肺栓塞患者血D-二聚体、B型钠尿肽、肌钙蛋白I、C反应蛋白的研究  

Study on blood DD,BNP,TnI,CRP in patients with acute pulmonary embolism

作　　者：邢国燕[1] 赵树波[1] 

机构地区：[1]吉林省通化市中心医院,吉林通化134001

出　　处：《中国当代医药》2016年第3期28-30,共3页China Modern Medicine

摘　　要：目的 探讨急性肺栓塞（APE）患者血D-二聚体（DD）、B型钠尿肽（BNP）、肌钙蛋白I（Tn I）和C反应蛋白（CRP）浓度变化与临床意义。方法 收集本院2013年6月~2015年6月收治的APE患者58例为实验组,同一时期随机选取50名医院体检中心健康体检者为对照组。分别进行DD、BNP、Tn I、CRP浓度检测;比较各组DD、Tn I、BNP、CRP浓度。结果 实验组DD、BNP、Tn I、CRP浓度较对照组高,两组比较差异有统计学意义（P〈0.01）。实验组DD、BNP、Tn I、CRP浓度较治疗有效组高,两组比较差异有统计学意义（P〈0.01）。实验组DD、BNP、Tn I、CRP浓度均值较治疗无效组高,两组比较差异无统计学意义（P〉0.05）。结论 联合检测DD、BNP、Tn I、CRP浓度对APE患者诊断、病情判断、疗效评价及预后的发展具有重要的临床意义。Objective To explore the concentration change and clinical meaning of DD,BNP,TnI and CRP in acute pul- monary embolism（APE） patients. Methods 56 APE patients from June 2013 to June 2015 of our hospital were selected as experimental group,and 50 healthy examined people at the same period of physical examination center were selected as control group.The concentration of DD,BNP,TnI and CRP was compared respectively.After treatment for 2 weeks, the concentration of DD,BNP,TnI and CRP in APE patients were compared with experimental group. Results The concen- tration of DD,BNP,TnI and CRP in experimental group was higher than that of control group respectively,and the difference was statistical significance（P〈0.01）.The concentration of DD,BNP,TnI and CRP in experimental group was higher than that of effectively treatment group respectively,and the difference was statistical significance （P〈0.01）.The concentration mean value of DD,BNP,TnI and CRP in experimental group was higher than that of ineffective treatment group respectively,while the difference between two groups had no statistical significance（P〉0.05）. Conclusion Combination detection the concentration of DD,BNP,TnI and CRP has great clinical meaning for diagnosis,condition judgment, effective evaluation and prognosis development of patients.

关 键 词：急性肺栓塞 D-二聚体 B型钠尿肽 肌钙蛋白I C反应蛋白 

分 类 号：R543.31[医药卫生—心血管疾病]