miRNA在牙再生领域的研究进展  

Research progress of miRNA in the field of tooth regeneration

作　　者：曹荣玉 王效英[1] 

机构地区：[1]山东省口腔生物医学重点实验室,山东大学口腔医学院牙体牙髓科,山东济南250012

出　　处：《口腔医学》2016年第1期94-96,共3页Stomatology

摘　　要：牙髓炎、牙周病和牙列缺损是口腔临床常见和多发性疾病,严重影响患者的口腔功能和容貌美观。目前,临床医生尚不能对病变的牙髓牙周组织及缺失的牙齿进行再生治疗。随着分子生物学和细胞生物学的发展,口腔再生医学可能会成为治疗口腔疾病的新方法。MicroRNA(miRNA)是一类内源性的小RNA,对牙齿发育和牙再生有重要的调控作用。该文就miRNA在牙再生领域的研究现状作一综述。Pulpitis,periodontal disease and dentition defect are common clinical diseases,seriously affecting the patients＇ oral function and appearance. Although conventional treatments can restore the oral function of patients to a certain extent,their long-term effects are poor. With the development of molecular biology and cell biology,oral regenerative medicine may become a new method for the treatment of oral diseases. miRNA is a kind of small endogenous RNA,which plays an important role in regulating tooth development and regeneration. This review presented recent advances in miRNA research and tooth regeneration.

关 键 词：MIRNA 牙再生 牙胚 

分 类 号：R342.3[医药卫生—基础医学]