母亲妊娠期和围生期因素与青少年血压的关系  

The relationship between maternal gestational and perinatal factors and blood pressure among adolescents

作　　者：李玉艳[1] 武俊青[1] 赵瑞[1] 任静朝[2] 戎芬[3] 周颖[1] 纪红蕾[1] 高尔生[1] 

机构地区：[1]上海市计划生育科学研究所/国家卫计委计划生育药具重点实验室,上海200032 [2]新乡医学院公共卫生学院流行病与卫生统计学教研室,河南新乡453003 [3]上海中医药大学基础医学院预防医学教研室,上海201203

出　　处：《中华疾病控制杂志》2016年第1期34-37,41,共5页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(81072364)

摘　　要：目的探讨母亲妊娠期因素和围生期因素与子女青少年期血压之间的关系。方法对1993-1995年无锡市建立的出生队列于2011-2013年（青少年期）进行随访，开展问卷调查、身高、体重和血压的测量，采用x。检验、多元线性回归分析、多因素二项式回归等统计方法进行数据分析。结果共随访到年龄16-18岁之间 的青少年2256人。调整性别、青少年期年龄、青少年期超重或肥胖、青少年期生活行为因素，将母亲妊娠期和围生期相关变量纳入多因素模型，结果显示：母亲产时有妊高症的对象，青少年期的收缩压和舒张压升高，“血压升高比例”增加（RR=1．54，95％CI：1．26～1．90）；随着出生身长的增加，青少年的收缩压升高。结论母亲产时妊高症是子女青少年期血压升高的危险因素，应采取一定的措施，控制妊高症的发生。Objective To explore the relationship between maternal gestational and perinatal factors and blood pressure （BP） among adolescents. Methods A follow-up study for the birth cohort from 1993 to 1995 in Wuxi was con- dueted during 2011 to 2013. Questionnaire survey and physical examination, including height, weight, systolic blood pres- sure （SBP） and diastolic blood pressure （DBP）, were conducted. The 2 test, multi-linear regression and muhi-genmod model were used to.analyze the data. Results A total of 2 256 adolescents aged from 16 to 18 were followed up. After ad- justing sex, age and overweight and obesity in adolescence, life habits of adolescents, the maternal gestational and perinatal factors were analyzed in the multi-models. We found that compared with adolescents whose mother had no pregnancy-in- duced hypertension iwhen delivery, those whose mother had pregnancy-induced hypertension had higher SBP, DBP and the proportion of elevated BP （RR = 1.54, 95% CI： 1.26-1.90）. And the SBP of adolescents increased along with the in- crease of birth body length. Conclusions Pregnancy-induced hypertension when delivery was a risk factor of blood pres- sure for adolescents. Some methods should be conducted to prevent the pregnancy-induced hypertension.

关 键 词：孕妇 青少年 血压 

分 类 号：R179[医药卫生—妇幼卫生保健] R544[医药卫生—公共卫生与预防医学]