416例药品不良反应报告回顾性分析  

Analysis of 416 Cases of Adverse Drug Reaction Reports

作　　者：张莉[1] 周鸣[1] 

机构地区：[1]南京医科大学第二附属医院临床药学室,江苏南京210011

出　　处：《中国药业》2016年第1期90-92,共3页China Pharmaceuticals

摘　　要：目的分析南京某三甲医院药品不良反应发生的特点,促进药物的合理使用。方法收集该院2013年至2014年416例有效不良反应报告,按患者性别、年龄、给药途径、药品种类、涉及器官或系统、不良反应类别、因果关系等方面进行统计分析。结果 416例不良反应报告中,60岁以上老年人最多,占43.27%;静脉滴注给药最多,占84.61%;抗菌药物最多,占53.33%;不良反应的临床表现以皮肤及其附件的损害多见,占43.94%。结论为保证用药安全有效,需加强药品不良反应的监测。Objective To analyze the characteristics and regularity of adverse drug reaction（ ADR） occurred in the hospital from 2013 to2014,and to offer some information about rational drug use and make the drug use more rationally. Methods 416 effective ADR case reports collected in the hospital by doctors and pharmacists were analyzed statistically in respect of patients＇ age and sex,route of administration,category of drug,organs and systems involved,and the clinical manifestation of the ADR. Results Among 416 ADR cases,aged over 60 years accounted for 43. 27%; 84. 61% were induced by intravenous dripping injection; the main clinical manifestations of ADR were lesions of skin and its appendages in 53. 33%; 43. 94% were induced by anti- infective drugs. Conclusion It is important to strengthen ADR monitoring and ensure safe medication.

关 键 词：药品不良反应 药品不良反应监测 合理用药 抗感染药物 

分 类 号：R969.3[医药卫生—药理学] R954[医药卫生—药学]