舒芬太尼用于剖宫产术后静脉自控镇痛35例  

Sufentanil Used for Patient Controlled Intravenous Analgesia after Cesarean Section in 35 Cases

作　　者：蒋永春[1] 张健[1] 成勤[1] 

机构地区：[1]江苏省海门市人民医院,江苏南通226100

出　　处：《中国药业》2016年第1期106-108,共3页China Pharmaceuticals

摘　　要：目的观察比较舒芬太尼与丁丙诺啡用于剖宫产术后静脉自控镇痛(PCIA)的效果及不良反应。方法将择期剖宫产术产妇70例随机分为舒芬太尼组和丁丙诺啡组,各35例。术后使用患者静脉自控镇痛(PCIA),于4,8,24,48 h进行视觉模拟评分(VAS)和Ramsay镇静评分,记录镇痛泵的有效按压次数,观察比较不良反应发生情况,回访镇痛效果。结果两组间VAS评分无显著差异,Ramsay评分和有效按压次数有显著差异,舒芬太尼组的主观满意度高于丁丙诺啡组(P<0.05),丁丙诺啡组的不良反应发生率高于舒芬太尼组(P<0.05)。结论舒芬太尼用于剖宫产术后PCIA具有与丁丙诺啡相当的镇痛效果,但不良反应的发生率低于后者,值得临床推广。Objective To compare the analgesic effect and adverse reaction of PCIA using sufentanil and buprenorphine in cesarean section. Methods 70 lying- in women of elective caesarean birth operation were randomly divided into 2 groups, including the sufentanil group of 35 cases and the buprenorphine group of 35 cases. And after the postoperative use of PCIA,score VAS and Ramsay at 4,8,24,48 h respectively to record analgesic pump＇s effective pressing number of times and to observe and compare and the adverse reactions,paying the return visit to the patients about the analgesic effect. Results There were no significant differences between the VAS scores of 2 groups, while there were significant differences in Ramsay scores and effective pressing number of time（ P〈0. 05）. The subjective satisfaction degree of the sufentanil group was higher than that of the buprenorphine group（ P〈0. 05）. And the adverse reactions of buprenorphine group occurred more than those of sufentanil group（ P〈0. 05）. Conclusion The analgesic effect of sufentanil applied in cesarean section postoperative PCIA is almost same with buprenorphine,but the adverse reaction incidence rate of the former is lower than the latter,thus sufentanil is suitable for clinical application.

关 键 词：舒芬太尼 丁丙诺啡 剖宫产 静脉自控镇痛 

分 类 号：R969.4[医药卫生—药理学] R971.2[医药卫生—药学]