女性泌尿生殖道支原体感染患者药敏状况  

Drug sensitivity analysis in female patients with genitourinary tract mycoplasma infections

作　　者：徐静[1] 陈冬梅[1] 赵辉[2] 海晓欧[1] 方芳[1] 王澜[1] 周园[1] 张迎今 

机构地区：[1]沈阳医学院病原生物学教研室,辽宁沈阳110034 [2]沈阳医学院附属第二医院,辽宁沈阳110002 [3]沈阳医学院,辽宁沈阳110034

出　　处：《中国微生态学杂志》2016年第2期222-224,共3页Chinese Journal of Microecology

摘　　要：目的探讨女性泌尿生殖道感染患者中支原体的感染状况及其对不同药物的敏感性,为临床合理用药提供参考。方法对516例女性泌尿生殖道拭子进行支原体培养,并对阳性菌株进行10种常用抗生素药敏试验。结果 516例患者中,支原体培养阳性263例,检出率为50.97%,其中解脲支原体(Ureaplasma urealyticum,UU)为237例(45.93%),人型支原体(Mycoplasma hominis,MH)仅9例(1.74%),UU+MH 17例(6.46%);三种类型感染均对交沙霉素、强力霉素、美满霉素比较敏感。结论 UU为沈阳医学院附属第二医院泌尿生殖道支原体感染的主要病原体,交沙霉素、强力霉素及美满霉素可作为治疗的经验用药,其中交沙霉素为首选抗生素。Objective To discuss the genitourinary tract infection rate and drug sensitivity in females and provide guidance for clinical rational use of drugs.Methods Urinary samples of 516 female patients initially diagnosed as genitourinary tract mycoplasma infection were collected and cultured.The positive bacterial strains were tested for antibiotic sensitivity.Results Mycoplasmas were detected in 263 out of the 516 samples.The positive rate of mycoplasma was 50.97%.Among the 263 samples,237cases were UU（Ureaplasma urealyticum）positive（45.93%）,9cases were MH（Mycoplasma hominis）positive（1.74%）,and 17 cases were both UU and MH positive（6.46%）.These mycoplasma strains were more sensitive to Josamycin,Doxycycline and Minocycline than to other antibiotics.Conclusion The genitourinary tract mycoplasma infections of our female patients are primarily caused by UU.Josamycin,Doxycycline and Minocycline can be used for treatment based on experience.Josamycin is the preferred choice of antibiotics.

关 键 词：泌尿生殖道 支原体 药敏试验 

分 类 号：R691.3[医药卫生—泌尿科学] R446.5[医药卫生—外科学]