不同反应温度和原料对化学沉淀法制备纳米羟基磷灰石的影响  

Effect of different reaction temperatures and reactant sources on hydroxyapatite nanoparticles synthesized in a precipitation process

作　　者：彭晗[1] 王磊[1] 田宇生 宋永猛[1] 吕珊珊[1] 

机构地区：[1]北京化工大学化学工程学院有机无机复合材料国家重点实验室,北京100029

出　　处：《北京化工大学学报（自然科学版）》2016年第1期19-25,共7页Journal of Beijing University of Chemical Technology(Natural Science Edition)

基　　金：北京化工大学高层次人才建设项目(12060029009/12060046001);中央高校基本科研业务费(YS1401);有机无机复合材料国家重点实验室基金(201311/201403002);国家自然科学基金青年科学基金(31400813)

摘　　要：使用不同磷源与钙源制得纳米羟基磷灰石,并利用X射线衍射、红外光谱、透射电镜、热重分析等分析手段对产物进行表征,探究不同的反应温度、不同原料等实验条件对产物的组成、形貌及尺寸的影响。结果表明:升高温度有利于晶体生长;不同钙源对产物的影响不大,改变磷源对产物组成的影响较大;产物羟基磷灰石中的磷酸根会被磷酸氢根所取代,并且以磷酸氢二钠为原料时产物中磷酸氢根含量最高。Nano-sized hydroxyapatite samples have been synthesized using different sources of calcium （Ca） and phosphorous （P） at different temperatures. The hydroxyapatite nanoparticles （nHAP） were characterized by X-ray diffraction （XRD）, Fourier transform infrared spectroscopy （FT-IR）, transmission electron microscopy （TEM） and thermogravimetric analysis （TGA） in order to investigate the effect of different reaction temperatures and differ- ent Ca and P sources. The results showed that higher reaction temperatures lead to better crystallization and larger particle sizes. Varing the calcium source had little effect, while different phosphorus sources led to changes in prod- uct composition, with some phosphate groups being replaced by hydrogen phosphate groups. The results showed that the product synthesized using disodium hydrogen phosphate had the maximum hydrogen phosphate content.

关 键 词：羟基磷灰石 纳米颗粒 钙源 磷源 

分 类 号：TQ126.3[化学工程—无机化工]