基于数据挖掘的杨秉秀治疗特发性男性不育症用药规律  

Study on Medication Regularity of Yang Bingxiu's Treatment for Idiopathic Male Infertility Based on Data Mining

作　　者：徐慧[1] 肖海鹏[1] 尹跃兵[1] 谢铭瑶[1] 符逢春[1] 乔江[2] 李强[1] 

机构地区：[1]湖南中医药高等专科学校,湖南株洲412000 [2]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《中国中医药信息杂志》2016年第2期25-29,共5页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：湖南省中医药科研计划项目重点课题(201222);全国老中医药专家(杨秉秀)传承工作室建设项目(2011年)

摘　　要：目的研究杨秉秀教授治疗特发性男性不育症的用药规律。方法收集杨秉秀教授门诊治疗特发性男性不育症病历,采用关联规则分析方法中的Apriori算法进行数据挖掘,对其处方中常用药物的类别、使用频次、药物间的关联规则等进行分析。结果收集病例46例,共计156诊次、156首处方,共使用中药78味、2710频次。使用频次最高的中药类别是补虚药,其次为利水渗湿药、清热药、收涩药。常用的药物配伍是补虚药+补虚药、补虚药+利水渗湿药、补虚药+清热药、利水渗湿药+利水渗湿药、利水渗湿药+清热药。结论杨秉秀教授治疗特发性男性不育症的组方用药,以补肾填精为主,益气健脾为辅,清热利湿化浊为佐,体现了补中有清、清中有补、补泻结合、标本兼治的治疗思路。Objective To study the medication regularity of Yang Bingxiu's treatment for idiopathic male infertility. Methods Outpatient records about idiopathic male infertility treated by Yang Bingxiu were collected. Apriori algorithm in association rules was used for data mining and analyzing the categories, usage frequency of commonly used medicine, and association rules among medicine. Results Totally 46 cases of records were collected, including 156 times of visits and 156 prescriptions. 78 kinds of Chinese materia medica were used with 2710 frequency. Chinese materia medica with the efficacy of tonifying deficiency was with the highest frequency, followed by medicine for diuresis and diffusing dampness, heat-clearing medicine and astringent medicine. The commonly used compatibility was tonifying-deficiency medicine + tonifying-deficiency medicine, tonifying-deficiency medicine + medicine for diuresis and diffusing dampness, tonifying-deficiency medicine + heat-clearing medicine, medicine for diuresis and diffusing dampness + medicine for diuresis and diffusing dampness, and medicine for diuresis and diffusing dampness + heat-clearing medicine. Conclusion Among the Yang Bingxiu's prescriptions for idiopathic male infertility, the main treatment is replenishing kidney essence, invigorating spleen and replenishing qi, and clearing heat and promoting diuresis, showing the treatment thoughts of tonifying within clearing, clearing within tonifying, reinforcing combining reducing, and treating both symptoms and root causes.

关 键 词：特发性男性不育症 名医经验 杨秉秀 数据挖掘 用药规律 

分 类 号：R2-05[医药卫生—中医学] R259.414