预见性护理在DC-CIK治疗原发性肝癌肺转移的价值  

The predictive nursing care of dendritic cell-cytokine induced killers in hepatocellular carcinoma with lung metastasis

作　　者：张静静[1] 邱玲云 胡耀仁[1] 付丽云[1] 

机构地区：[1]宁波市第二医院肝病科,浙江宁波315000

出　　处：《中国现代医生》2016年第1期138-141,145,共5页China Modern Doctor

基　　金：浙江省病理生理学技术研究重点实验室开放基金(201501);浙江省宁波市自然科学基金项目(2015A610236)

摘　　要：目的探讨原发性肝癌肺转移患者行自体树突状细胞和细胞因子诱导的杀伤细胞（DC-CIK）治疗的预见性护理效果。方法选择2013年5月~2015年5月期间49例进行DC-CIK治疗的原发性肝癌肺转移患者,随机分为干预组24例和对照组25例;对照组给予常规性护理,干预组在此基础上给予预见性护理,比较两组治疗前后卡氏体力状况评分、治疗期间不良反应有无差异。结果干预组与对照组的Karnfsky评分在治疗后及治疗后1周差异均存在统计学意义（P〈0.01）。除发热外,干预组在DC-CIK治疗期间的不良反应发生率与对照组比较明显下降（P〈0.05）。结论将预见性护理应用到原发性肝癌肺转移患者的DC-CIK治疗中有积极的意义。通过采取预见性护理,提高了患者的生活质量,从而体现了护士的自我价值。Objective To evaluate the efficacy of predictive nursing care on hepatocellular carcinoma with lung metastasis patients during dendritic cell-cytokine induced killers treatment. Methods A total of 49 patients suffered from hepatocellular carcinoma with lung metastasis from May 2013 to May 2015 were randomly divided into intervention group and control group. Control group（25 cases） were given routine nursing care. Except for routine care, Intervention group（24 cases） were given predictive nursing care. Karnfsky score before and after treatment, adverse reactions during treatment were observed. Results Karnfsky score after treatment and one week after treatment had been significantly different between intervention group and control group（P〈0.01）. In addition to fever, the incidence of adverse reactions were obviously decreased compared intervention group with control group（P 0.05）. Conclusion Applying predictive nursing care to hepatocellular carcinoma with lung metastasis patients in DC-CIK treatment has a positive meaning.Due to adopt predictive nursing care, treatment were successfully completed, improved the patient＇s quality of life, and embodied the nurse self-worth.

关 键 词：预见性护理 DC-CIK细胞 原发性肝癌 转移 

分 类 号：R473.7[医药卫生—护理学]