肝硬化患者肺部感染相关危险因素研究  被引量:7

Risk factors of nosocomial pulmonary infections in patients with liver cirrhosis

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作  者:王飞[1] 李晓鸥[1] 张静[2] 

机构地区:[1]杭州市西溪医院杭州市第六人民医院肝病科,浙江杭州310000 [2]宁波大学医学院临床医学系,浙江宁波310058

出  处:《中华医院感染学杂志》2016年第4期758-760,共3页Chinese Journal of Nosocomiology

基  金:浙江省医药卫生科技计划基金资助项目(2012YCG147)

摘  要:目的研究与分析肝硬化患者发生肺部感染的相关因素,以期对肝硬化患者肺部感染的预防制定相关措施。方法选取2012年7月-2015年7月3 610例肝硬化患者中244例发生肺部感染的患者作为研究对象,对其相关因素进行单因素和多因素分析。结果 3 610例肝硬化患者中发生肺部感染244例,感染率为6.76%;有34例肺部感染患者送检标本中共分离出病原菌20株,主要为大肠埃希菌占35.0%;通过相关因素分析显示,低蛋白血症、抗菌药物的不规范应用、Child-pugh C级、住院时间、侵入性操作、高龄等为肝硬化患者发生肺部感染的相关因素。结论肝硬化患者发生肺部感染是由多种危险因素引起,医护工作人员医治患者时,应注意规范操作,患者应注意个人卫生,以减少肺部感染的发生。OBJECTIVE To study and analyze the related factors of pulmonary infections in patients with liver cirrhosis,and to propose the related measures to prevent the infections.METHODS Totally 244 patients who had pulmonary infections among the 3610 patients with liver cirrhosis during Jul.2012 to Jul.2015 were selected as subjects and the related factors were analyzed by single factor analysis and multi-factor analysis.RESULTS There were244 cases of pulmonary infections among the 3 610 patients with liver cirrhosis and the infection rate was 6.76%.Totally 20 strains of pathogens were separated from the delivered specimens of 34 cases of pulmonary infections and the main pathogenic bacteria were Escherichia coli accounting for 35.0%.The analysis of related factors showed that hypoproteinemia,incorrect use of antibacterial drugs,Child-Pugh class C,time of hospitalization,invasive operation,advanced age,etc.CONCLUSIONPulmonary infections in liver cirrhosis patients are caused by multiple risk factors.Health care workers should pay attention to standard operation when treating patients and patients should be pay attention to personal hygiene in order to reduce occurrence of pulmonary infections.

关 键 词:肝硬化 肺部感染 危险因素 预防措施 

分 类 号:R373.2[医药卫生—病原生物学]

 

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